An antibody is a glycoprotein that can perform specific binding with antigen and has many immunologic functions; it is a plasma cell produced by B-cells after being subject to antigenic stimulation and through a process of proliferation and differentiation.顺便提供更详细的资料给您:An an...
IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential ...
P-Glycoprotein Antibody (MA1-26528) in WB Western blot was performed using Anti-P-Glycoprotein Monoclonal Antibody (C219) (Product # MA1-26528) and due to glycosylation, 160-230 kDa band corresponding to ABCB1 was observed across cell lines tested except MCF-7 which is reported to be negat...
TROPHOBLAST GLYCOPROTEIN IS A NOVEL TARGET FOR ANTIBODY THERAPY IN PROSTATE CANCERBrachial ArteryEndothelial DysfunctionErectile DysfunctionPhosphodiesterase InhibitorsPolyarteritis NodosaSildenafilTestisAlthough management of warfarin is challenging for patients with chronic kidney disease (CKD), no prospective ...
In addition to chemokines,ASC attachmentto bone marrow endothelium is likely to requireselectinsand/orintegrins. ASCs upregulate expression of P-selectin glycoprotein ligand (PSGL)-1, a protein that can be modified to display both P- and E-selectinbinding sites(Xia et al., 2002). In in vitr...
TF encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of transferr...
PD-1 is a glycoprotein that contains four putative N-linked glycosylation sites in its extracellular IgV domain. Studies evaluating PD-1 fucosylation revealed that the four sites of PD-1 (N47, N58, N74, and N116) are all glycosylated, and glycosylation is linked with the functional localizat...
Belantamab mafodotin also known as GSK2857916, is a novel ADC composed of a humanized FC modified anti-BCMA mAb coupled with cytotoxic agent MMAF through a non-cleavable maleimidocaproyl (mc) linker. Belantamab mafodotin has an average DAR of 4. BCMA is a transmembrane glycoprotein specif...
CD90.2 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90.2 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. Thy 1 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other even...
Thyroid peroxidase(TPO) is a membrane-associatedglycoproteinthat catalyzes the iodination oftyrosine residuesand their coupling to form thethyroidhormonesT3and T4, in a process known as organification. Anti-TPO antibodies may be found in the presence andabsenceofautoimmune thyroid disease. In studies ...