Glycoprotein antigens SIMA135 that is expressed in metastatic human tumor cellsThe invention provides a protein that is a tumor marker protein. This protein can be used to prepare antibodies that bind to the tumor marker protein. These antibodies can be used to reduce, or eliminate metastasis by...
Developmental expression of the axonal glycoprotein TAG-1: differential regulation by central and peripheral neurons in vitro TAG-1 is a 135,000 Mr axonal glycoprotein of the immunoglobulin superfamily that promotes axon extension in vitro. One distinguishing feature of TAG-1 is i... D Karagogeos...
Carcinoembryonic antigen (CEA) has been recently implicated in the process of human colon cancer liver metastasis by means of an adhesion mechanism. Based on the strong sequence and structural homology of biliary glycoprotein (BGP) to CEA, we hypothesized that BGP might be overexpressed at the RNA...
Sm25, a major antigen in the surface tegument of the parasitic helminth Schistosoma mansoni, is a 25 kDa N-glycosylated glycoprotein which co-purifies with isolated surface membranes and behaves as an integral membrane protein in Triton X-114 (TX-114). The deduced amino acid sequence of Sm25...
In one embodiment, these antigens may be produced by a baculovirus expression vector and form virus-like particles (VLPs). The antigens are useful as diagnostic reagents in diagnostic methods and kits for determining infection of an individual with HEV. The antigens are also useful in vaccine ...
Proteolytic cell surface release (‘shedding’) of the prion protein (PrP), a broadly expressed GPI-anchored glycoprotein, by the metalloprotease
CHI3L1(Chitinase-3-like protein 1)|GP39|Glycoprotein 39|Cartilage|YKL-40|ASRT7|CGP-39|HC-gp39|YYL-40Human CHI3L1(Chitinase-3-like protein 1) ELISA KitCHI3L1CHI3L1(Chitinase-3-like protein 1)|GP39|Glycoprotein 39|Cartilage|YKL-40|ASRT7|CGP-39|HC-gp39|YYL-4037.5pg/ml62.5-4000pg/ml Sand...
The anti-angiogenic His/Pro-rich fragment of histidine-rich glycoprotein binds to endothelial cell heparan sulfate in a Zn2+-dependent manner The plasma protein histidine-rich glycoprotein (HRGP), which has been identified as an angiogenesis inhibitor, binds to heparan sulfate (HS) in a Zn(2+)...
Antigen targeted therapy Hedgehog (Hh) signaling pathway Hh is a key pathway required for the survival of leukemia stem cells which can be disturbed by specific inhibitors. Glasdegib, an oral Hh pathway suppressor, has demonstrated a strong suppression effect on the proliferation of AML cells [18...
Antigens used for recall were HAs expressed in HEK293 cells (Sino Biological: H1 Cal09, Cat. No. 11055-V08H; H5 VN04 Cat. No. 11062-V08H2; and H7 AH13 Cat. No. 40103-V08H) as well as Ebola virus glycoprotein expressed in insect cells (IBT BioServices Cat. No. 0501-015). ...