Defining antibody-antigen recognition: towards engineered antibodies and epitopes. Int Rev Immunol. 1991; 7 (2):165–188.Tainer JA, Deal CD, Geysen HM, et al. Defining antibody-antigen recognition: towards engineered antibodies and epitopes. International Review of Immunology 1991; 7: 165 -188....
A process in which an effector cell of the immune system (such as a natural killer cell, a macrophage, a neutrophil or an eosinophil) actively lyses a cell whose membrane surface antigens have been bound by antibodies. The crystallizable fragment (Fc) portion of the antibody allows the immu...
For the design of immunogens that expose occluded epitopes in novel molecular contexts, we and others previously described the development of “epitope scaffold” proteins15,16,17. These molecules are engineered by transplanting the structure of the antibody-bound epitopes from viral molecules onto unr...
antigen原;monoclonal单克的;peptide肽;antigens原;polypeptide多肽;recombinant重组器官;albumin白蛋白,清蛋白;reagent试剂;assay试验;peptides多肽类;reagents试剂; 词组| 习惯用语 monoclonal antibody 单克 polyclonal antibody 多克 neutralizing antibody [医]中和 maternal antibody 母 fluorescent antibody 荧光 英语例句...
High sensitivity verified by inactivated virus sample and antigens The two antibodies (NUN-CH14/NUN-CH15) bind at different epitopes of the SARS-CoV-2 nucleocapsid protein, significantly improving the efficiency of antigen detection. The antibody pairs can detect the inactivated virus sample at 1:...
Antibodies purified from an MS brain plaque were panned by phage display peptide libraries to discern potential antigens. Phage displaying peptide sequences resembling Epstein-Barr Virus Nuclear Antigens 1 & 2 (EBNA1 & 2) epitopes were identified. Antibodies from sera and CSF from other MS patien...
Research into bispecific antibodies, which are designed to simultaneously bind two antigens or epitopes, has advanced enormously over the past two decades. Owing to advances in protein engineering technologies and considerable preclinical research efforts, bispecific antibodies are constantly being developed ...
Evaluation of chimeric antigen receptor (CAR) expression following transduction is a critical step in the production of CAR-T and CAR-NK cells for cancer immunotherapy. To simplify CAR detection, R&D SystemsTMfluorescent-labeled proteins bind directly to single chain variable fragment (scFv) CAR T ...
. An antigen may have one or more than one epitope. The specific reaction referred to above is meant to indicate that the antigen will react, in a highly selective manner, with its corresponding antibody and not with the multitude of other antibodies which may be evoked by other antigens....