Keywords: antibodies and 尾 lymphocytes; immunoglobulin structure; biological effector functions of immunoglobulins; immunoglobulin receptors; cellular basis of antibody production; immunoglobulin genes and antibody diversity; specificity of antibodies-tools in diagnostics and therapy; BcR heavy chains and Ig ...
Keywords: antibodies and β lymphocytes; immunoglobulin structure; biological effector functions of immunoglobulins; immunoglobulin receptors; cellular basis of antibody production; immunoglobulin genes and antibody diversity; specificity of antibodies-tools in diagnostics and therapy; BcR heavy chains and Ig ...
also called isotype. The various antibody classes are found in different compartments of the body. For example, IgA is present in the saliva while IgG and IgM are found in the blood. In addition, membrane-bound antibodies are also found (e.g.: IgE on mast cells or IgD on B lymphocytes...
For a better understanding of the immune defence reactions performed by fish against pathogens, a broad knowledge on the biology of lymphocytes is required. Humoral and cellular reactions are driven in vertebrates by mononuclear leucocytes (Roitt et al., 1993), and in teleosts humoral activities ...
Ro/SS-A- and La/SS-B-reactive B lymphocytes in peripheral blood of patients with Sjgren's syndrome The aim of this study was to investigate the production of anti-Ro/SS-A and anti-La/SS-B antibodies in peripheral blood (PB) of patients with Sjgren's synd... HALSE,WAHREN‐HERLENIUS...
Table 3 Current status of innovative antibody, Fc fusion protein, and chimeric antigen receptor (CAR) drug candidates* Full size table Figure 1 Cartoons of molecules and constructs discussed. (A) IgG monoclonal antibody; (B) FAb fragment; (C) Single chain fragment, variable (scFv); (D) Hete...
We conducted a double-blind, placebo-controlled study of 40 patients (aged 19 to 60 years) with clinical definite relapsing remitting (RR) MS and brain MRI... Achiron,Gabbay,Gilad,... - 《Neurology》 被引量: 485发表: 1998年 AUTOREACTIVITY BY DESIGN: INNATE B AND T LYMPHOCYTES. Innate ...
Steinman, Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release. J Exp Med, 1984. 160: 1717–35. CrossRef Croft, M. and S.L. Swain, B cell response to fresh and effector T helper cells. Role of cognate ...
G. The functional network of ion channels in T lymphocytes. Immunol. Rev. 231, 59–87 (2009). CAS PubMed PubMed Central Google Scholar Feske, S., Wulff, H. & Skolnik, E. Y. Ion channels in innate and adaptive immunity. Ann. Rev. Immunol. 33, 291–353 (2015). CAS Google ...
MAb to LTα gave strong reactivity on lymphocytes in active MS lesions and weak reactivity on microglia within lesion areas. These results show that mAb to LTα and LTβ recognize different cell types within the CNS. Furthermore, individual mAb against LTβ were capable of distinguishing between...