The use of the dermal substitute biodegradable temporizing matrix (BTM) is being evaluated to promote wound stabilization in the presence of severe soft tissue necrosis, a well-known characteristic of xylazine wounds. The role of antibiotics in the treatment of BTM placement for xylazine wounds is ...
into the treatment groups. To generate wounds, the rats were anaesthetized by intraperitoneal injection of 100 mg kg−1ketamine + 10 mg kg−1xylazine and the dorsal side of the rats was shaved with electrical clippers and then depilated with Nair. The exposed skin was wiped ...
On day 10, the wound size for the combo-treated group was significantly smaller than that in the control or in the other treatment groups (p < 0.005), and the median wound size on day 10 for the combo group was less than the median wound size on day 0, meaning the wounds had begun...