The heterogeneity of atypical wounds can present diagnostic and therapeutic challenges; however, as the prevalence of atypical wounds grows worldwide, prompt and accurate management is increasingly an essential skill for dermatologists. Addressing the underlying cause of an atypical wound is critical for ...
The rabbits were allowed to acclimatize for 1 week before experimentation and were fed 150 g/day of LRC4 (Oriental Yeast, Co., Tokyo, Japan). Forming the wound surface and NPWT A mixture of 1.5 mL of ketamine and 1.0 mL of xylazine was injected intramuscularly and guided under very deep...
Mice were anesthetized by a mixture of xylazine (0.01 mg/g) and ketamine (0.08 mg/g), followed by pupil dilation with tropicamide (Akorn, Somerset, New Jersey) and phenylephrine. A 577-nm PASCAL laser (Topcon Medical Laser System, Inc., Santa Clara, CA) assisted by a slit-lamp system ...
For anesthesia for surgical procedures as well as wound measurements mice received an intraperitoneal (i.p.) injection of 100 µl solution containing 2.215 mg of ketamine and 0.175 mg of xylazine hydrochloride. At the set time points animals were euthanized by cervical dislocation25. No other ...
All rabbits were anesthetized via intramuscular injection xylazine (3 mg/kg body weight) and ketamine (30 mg/kg body weight) combination. Prior to the experiment, the animals were accustomed to environment about one week and all animals were fasted for 12 h before the operation. A circu...
Twelve Male Sprague–Dawley rats (6–8-weeks-old) were purchased from Beijing Charles River Biotechnology, anesthetized with intramuscular injections of ketamine (10%, 75 mg/kg BW) and xylazine (2%, 10 mg/kg BW) (both from Alfasan Co., Woerden, Holland), and surgery was performed under ...
Thirty male Sprague-Dawley rat (n = 30, wt. = 180 ± 5 g) were anesthetized with Ketamine (80 mg/kg) + Xylazine (15 mg/kg) IP. The back of each rat was shaved with care to avoid traumatizing skin before procedural wounding. The shaved backs were thoroughly...
24 All animal protocols were approved by Northwestern University Animal Care and Use Committee. Twenty rabbits were divided into ischemic and nonischemic groups. Rabbits were anesthetized with ketamine hydrochloride (60 mg/kg) and xylazine hydrochloride (5 mg/kg) prior to surgery. In the ischemic ...
An intraperitoneal injection of ketamine/xylazine was used to anesthetize the SD rats and the rats (UNC IACUC Protocol No: 23-029.0) were kept unconscious while ventilating at a volume of 7.5 ml/kg (typical for rodent studies106) with isoflurane and oxygen (after tracheotomy). The lungs ...
of a mixture of xylazine/ketamine (XK) (5 mg/kg i.p.; 50 mg/kg i.p.) was used to anesthetize the rats (Ritschl et al. 2015). On the backs of these rats, dorsal hair was completely removed. First, hair was cut with clippers, and then a chamomile-enriched hair removal cream ...