Antibiotics show a clinical benefit whenused for the treatment of pouchitis. The downsidesof antibiotic treatment, especially with recurrent orprolonged courses such as used in inflammatory boweldisease, are significant side effects that often causeintolerance to treatment, Clostridium dificile infection,...
In a studypublishedinScience Advances, Dr. Shai Bel and his research team at the Azrieli Faculty of Medicine of Bar-Ilan University have uncovered crucial insights into how antibiotic use increases the risk of inflammatory bowel disease (IBD). The study demonstrates that antibiotics interfere with ...
Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 Antibiotics use, particularly antibiotics with greater spectrum of microbial coverage, may be associated with an increased risk of new-onset inflammatory bowel dis...
Bowel inflammation in cancer patients: the microbiome, antibiotics and interleukin-9Microbiome composition can impact disease courses and also immunotherapy outcomes in solid tumours. It is still unclear how the microbiome might impact treatments in oncology, but also how modulation via antibiotics might ...
The common prophylactic therapy for bowel surgery is ineffective for clearing Bacteroidetes, the primary inducers of systemic inflammation, and causes fast... The role of secreted gut microbial components in the initiation of systemic inflammation and consequences of antibiotic therapies on this inflammator...
Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal (GI) disorder. Increasing evidence implicates the GI microbiota in IBS pathogenesis and its modulation represents an emerging therapeutic strategy. Original and review articles were identified through selective searches performed ...
The book covers basic research like effects on bacteria, anti-inflammatory and mucoregulatory effects, but also clinical results with up-to-date information for the use of such medications to potentially treat diseases as diverse as chronic airway diseases, arthritis, inflammatory bowel disease, and ...
in the presence of inflammatory bowel disease, the oral pathogenic bacteria Klebsiella and Enterobacter proliferate abnormally and colonize the gut, aggravating gut inflammation.15Therefore, we hypothesized that systemic inflammation caused by experimental periodontitis and ectopic colonization of the oral micro...
Crohn’s disease is aninflammatory bowel disease(IBD). It’s characterized by chronic inflammation in the digestive tract. There’s no cure for Crohn’s, but medications including antibiotics may help manage the disease. Antibiotics are medications used to treat or prevent infections caused by bact...
given to babies and young children, when the immune system is still developing, to inflammatory bowel disease, asthma, psoriasis and other inflammatory diseases later in life," said Dr. Mann, who is based at the University's newly launched Lydia Becker Institute of Immunology and Inflammation. ...