Expression of VIM-2 leads to physiological trade-offs for bacterial pathogens that can be exploited to treat infections caused by multidrug-resistant bacteria. Megan M. Tu Lindsey A. Carfrae Eric D. Brown Research02 Jan 2025Nature Microbiology ...
The emergence of antimicrobial resistance, the main cause of morbidity and mortality from otherwise treatable infections, is largely attributed to the inappropriate use of antimicrobials. However, data on the extent of inappropriate use of antibiotics in the community is scarce in Ethiopia. The aim of...
18,20-25,27-29 However, little is known about whether parents influence prescribing choices when they directly or indirectly communicate their desire for antibiotics or whether physicians can effectively communicate reasons for not prescribing antibiotics inappropriately while maintaining satisfaction. This ...
Bacterial resistance to antimicrobials is an emerging problem worldwide due to ineffective durations of therapy and inappropriate antimicrobial choices. It is a challenge that is associated with high morbidity and mortality rates. Furthermore, MDR bacteria are causing infections to become untreatable with...
It was estimated that antibiotic resistant infections were responsible for 1.27 million deaths in 2019 [2]. Without urgent action, the figure is projected to reach 10 million deaths every year by 2050 [1]. Moreover, antibiotic resistant bacteria are spreading within and between different ecosystems...
In primary care, prescribing unnecessary antibiotics for acute respiratory infections (ARIs) is a common, inappropriate service. Clinicians may prescribe unnecessary antibiotics—again, the easy, safe option—due to perceived or explicit patient demand, a desire to do something meaningful for patients, ...
However, the pattern of coefficients on the monthly dummies shown in Figure B-1 in the appendix shows the demand increases in winter months, perhaps due to a preference for using antibiotics to treat respiratory tract infections, and virus-induced secondary bacterial infection in cold seasons (...
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Infections and SepsisA Themed Issue in Honor of Professor Jordi Vila—Outstanding Contributions in the Fields of Antimicrobial ResistanceA Themed Issue in Honor of Professor Richard Proctor—Outstanding Contributions in the Fields of Persistent Staphylococcus aureus InfectionsActinomycetes: The Antibiotics ...
aureus) are the two most common types leading to acute and chronic pulmonary infections [1,7,8]. Inflammatory responses triggered by infection, damage pulmonary structures, resulting in declined lung function, pulmonary exacerbations, bronchiectasis, pulmonary insufficiency, and eventually respiratory ...