Understanding the molecular mechanisms that bacteria use to resist the action of antimicrobials is critical to recognize global patterns of resistance and to improve the use of current drugs, as well as for the design of new drugs less susceptible to resistance development and novel strategies to ...
You might find these chapters and articles relevant to this topic. Biological Development and Physical Health Bethany A.Wattles,Michael J.Smith, inEncyclopedia of Child and Adolescent Health (First Edition), 2023 Antibiotic resistance Antibioticresistance is a growingpublic healththreat; resistant bacteria...
Article 21 August 2023 Efflux pump-mediated resistance to new beta lactam antibiotics in multidrug-resistant gram-negative bacteria Article Open access 29 August 2024 References Walker, D. & Fowler, T. Annual Report of the Chief Medical Officer: Volume Two, 2011: Infections and the Rise of...
Antibiotic resistanceis the term to describe the resistance of bacteria to the action of antibiotics. Over the years, there has been rapid evolution ofantibioticresistance, killing thousands of people annually (Pehrsson et al., 2016; Laxminarayan et al., 2013). Resistance to both naturally occurri...
Leading articles. Antibiotic resistanceFinchRGingentaconnectJournal of Antimicrobial Chemotherapy
Importantly, since this compound class is completely new and the protein LpxH has not yet been exploited as a target for antibiotics there is no pre-existing resistance to this class of compounds. This is in contrast to the many ‘me-too’ antibiotics of existing classes currently in clinical...
However, the first step is to determine the safety of this species as regards the potential spread of antibiotic resistance genes. Since there is only a limited number of articles dealing with the antibiotic resistance of the species L. amylovorus, we have decided to study its safety in ...
Figure S3: Gene organization of tetracycline resistance genes (yellow) with transposase ISAs31 and transposition protein TnsC (brown) as well as Type 1 restriction recognition sites subunits (orange) that drives horizontal gene transfer determined in A. rivipollensis G87 genome. The CDS were ...
such methods could not provide an accurate epidemiological aspect and a genetic basis of antimicrobial resistance leading to an inappropriate antibiotic administration. Hybrid genome assembly is a combination of short- and long-read sequencing, which provides better genomic resolution and completeness for ...
genes encoding antibiotic resistance by production of an inactivating enzyme or by an altered intracellular target [27,52,121]. However, it is important to note that articles referring to cross-resistance and co-resistance often describe pathogens with QAC tolerance combined with antibiotic resistance....