The Journal of Antibiotics (2017) 70, 520–526 & 2017 Japan Antibiotics Research Association All rights reserved 0021-8820/17 www.nature.com/ja REVIEW ARTICLE The antibiotic resistance crisis, with a focus on th
Yet, as the gut microbiome is a complex ecological network of microorganisms, the effects of antibiotics can be highly variable. With the advent of multi-omic approaches for systems-level profiling of microbial communities, we are beginning to identify microbiome-intrinsic and microbiome-extrinsic ...
Moreover, cabazitaxel, another semisynthetic taxane with a similar structure to docetaxel, is sold under the trade name Jevtana. Cabazitaxel has similar mechanism of action as docetaxel and was approved by the FDA in 2010. It is often used in combination with prednisone, an anti-inflammation ...
Summary The indications for prophylactic antibiotics in surgery have been studied intensely over the past few years, and consensus is beginning to emerge in three main areas鈥攖he type of patient that requires prophylactic agent, the type of agent that should be given and its duration. It is ...
The sequencing data were processed beginning with raw read filtration using SOAPnuke v1.5.2, followed by alignment to the reference genome via HISAT2 v2.0.4 and Bowtie2 v2.2.5. Gene expression quantification was performed with RSEM v1.2.8. For comparative analysis, PCA was employed to disting...
Beginning in 2015, a 15-month national shortage of a commonly prescribed antibiotic, piperacillin/tazobactam, known by the brand name Zosyn, provided a unique opportunity to compare rates of death in hospitalized patients with sepsis who were administered two different types of antibiotics—one that ...
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome is a complex ecological network of microorganisms, the effects of antibiotics can be highly variable. With the advent of multi-...
Endophytes co-evolved with plants since the beginning of their land existence and carried out several of their traits as secondary metabolite production and their fight against environmental stresses and attacking path- ogens (Kealey et al. 2017). Many of these pathogens need colonization and QS...
接种两个MH-A板后,用链球菌组G菌株,在一个板的表面放置一个抗生素的E测试条。然后,如所示,在第二个板上放置另一种抗生素的E测试条。使用塑料接种回路,在各自板的表面标记每种抗生素的MIC值。接下来,覆盖盘子,在室温下孵育一小时。在此之后,使用钳子卸下 E 条。接下来,收集一个板和一个电子测试条,用于另一...
control is achieved by placing antibiotic discs at the interface between inocula of the test and control bacteria on the same plate. In this way the zone of inhibition obtained with the test organism can be compared directly with that of a known control, and variations in the cultural conditio...