Lata S, Mishra NK, Raghava GP. AntiBP2: improved version of antibacterial peptide prediction . BMC Bioinformatics 2010; 11 ( Suppl 1 ) :S19.Lata S, Mishra NK, Raghava GP: AntiBP2: improved version of antibacterial peptide prediction. BMC bioinformatics 2010, 11 (Suppl 1) : S19. PubMed...
Antibacterial peptides are important components of the innate immune system, used by the host to protect itself from different types of pathogenic bacteria. Over the last few decades, the search for new drugs and drug targets has prompted an interest in these antibacterial peptides. We analyzed 4...
Antibacterial peptides are important components of the innate immune system, used by the host to protect itself from different types of pathogenic bacteria. Over the last few decades, the search for new drugs and drug targets has prompted an interest in
The prediction showed that this peptide form alpha helices and it may have at least three residues on the same hydrophobic surface, and may interact with membranes and has a chance to be an AMP. Peptides were synthesized using solid-phase methodology with Fmoc- protected amino acids (GL ...
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GSK1322322 is a potent inhibitor of peptide deformylase and novel hydrazinopyrimidine with in vitro antibacterial activity against common skin and respiratory tract pathogens. An evaluation of the intrapulmonary penetration of GSK1322322 into ELF and AM was performed in 17 healthy adults [123]. Subjects...
乳酸链球菌素(Nisin)是由乳酸链球菌产生的一种小分子抗菌肽,具有高效的抑菌性能。研究表明Nisin可抑制口腔致龋菌生长,抑制戈登链球菌、变异链球菌、血链球菌3种混合菌生物膜的形成,并且与人类口腔上皮细胞相容性高,不具有细胞毒性[11]。Nisin生物安全性高、不易导致口腔菌群失调和产生耐药性等优点使其在口腔领域具有良好...
Bioactivity and bactericidal mechanism of histidine-rich beta-hairpin peptide against gram-negative bacteria. Int J Mol Sci. 2019;20:16. Google Scholar Xu W, et al. Design of embedded-hybrid antimicrobial peptides with enhanced cell selectivity and anti-biofilm activity. PLoS ONE. 2014;9(6):...
et al. Potentiation of antibiotic activity by a novel cationic peptide: potency and spectrum of activity of SPR741. Antimicrob. Agents Chemother. 61, e00200–e00217 (2017). CAS PubMed PubMed Central Google Scholar Fleischmann, W. A., Greenwood-Quaintance, K. E. & Patel, R. In vitro ...
J. et al. N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity. Antimicrob. Agents Chemother. 46, 2752–2764 (2002). CAS PubMed PubMed Central Google Scholar Payne, D. J. et al. Discovery of a novel and potent class of FabI-...