抗心肌缺血药 antianginal agents 抗心绞痛药 AntianginalAgents 张政中南大学药学院药理学系 什么是心绞痛?由于冠状动脉供血不足→心肌急剧、暂时的缺血与缺氧所引起的临床综合征缺血性心肌病的常见症状典型症状:突然发生的胸骨后紧缩或压榨性疼痛向左前胸区和左上肢放射发作原因:心肌氧的供需平衡失调急剧、暂时缺血...
agents.Ital tersgl ucoseandfattyaci d m etabol i sm .Cl i ni calstudi es have dem onstrated theeffi cacyandsafetyof ranol azi ne i n the treatm ent of chroni cangi na pectori s,ei therasm onotherapyor i n com bi nati on w i th otheranti angi nal agents.Thecom m on ...
Chapter 7. Antianginal Agentsdoi:10.1016/S0065-7743(08)60802-7C. F. SchwenderAnnual Reports in Medicinal Chemistry
This review of studies on anti-anginal agents and their use in the anginal syndrome shows nitroglycerin to be unsurpassed in clinical effectiveness. It has a rapid onset of action. Its duration of action is relatively short but the need for a more prolonged effect has not been demonstrated. ...
Chapter 5. Antiarrhythmic and Antianginal AgentsCardiac arrhythmias result from the changes in the conducting properties and automaticity of the myocardium. Each cardiac impulse arises in the sinoatrial node in the right atrium, and then is rapidly transmitted throughout the atria and via the ...
Of pirazolopirmidinona antianginal agents. Are compounds of formula (i) in which R IS h, alkyl C High 1, sub sub cicloalquil 1 - C 3, C 5 or C 3 - sub sub sub sub Perfluoroalkyl C 1 - C 2 (Squared);... AS Bell,D Brown,NK Terrett 被引量: 0发表: 2015年 Dihidropirazo...
Attacks of angina can be precipitated by increasing the heart's oxygen demand or by decreasing its supply. As for drug therapy of angina pectoris, the use of agents believed to be coronary vasodilators has traditionally been involved in an effort to increase coronary blood flow (CBF). Some ag...
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Others: methaemoglobinaemia(高铁血红蛋白) Tolerance : avoiding steady-state plasma concentration; supplement of agents containing –SH (captopril) ;2.1 Other nitrates Isosorbide dinitrate (硝酸异山梨酯) Isosorbide-5-mononirate (5-硝酸异山梨酯) Compared with nitroglycerin: Similar but weaker effect ...