Disclosed is a nanobody against the human programmed death factor PD-LI. The antibody has the function of blocking the binding of PD-LI to the receptor PD-I. Disclosed are the nanobody and the gene sequence encoding the nanobody, the corresponding expression vector and the host cell capable...
Total GDF-15 levels (free GDF-15 plus visugromab-GDF-15 complex) during treatment were determined by a validated ECL method, using a custom visugromab non-competitive anti-GDF-15 nanobody as a capture reagent and, following saturation with visugromab, a custom non-competitiv...
Anti-Human GPC3 Nanobody (HN3) 价格: ￥2300/支 产品详情:Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professio... 包装规格:100μg 用途:仅用于科研 用途:仅用于科研 货号:RHE84603 品牌:AntibodySystem 产地:France Anti-Human CF...
The term “heavy-chain single-domain antibody”, “VHH domain”, “VHH”, “VHH antibody fragment”, “VHH antibody” and “nanobody” are used interchangeably. The term “IMGT numbering system” is an integrated information system dedicated for immunoglobulins (IGs), T cell receptors (TCRs) ...
PD-L1/Toll-like receptors (TLR) 7 dual-targeting nanobody-drug con- jugate composed of anti-PD-L1 nanobody and TLR7 agonists reshaped tumor immune microenvironment, increase CD8+ T cells infiltration and stimulated NK cells activation [203]. Nanovesicles derived from M1 mac- rophages ...
(free GDF-15 plus visugromab-GDF-15 complex) during treatment were determined by a validated ECL method, using a custom visugromab non-competitive anti-GDF-15 nanobody as a capture reagent and, following saturation with visugromab, a custom non-competitive anti-visugromab antibody as a ...
Nanobody-based cancer therapy of solid tumors Nanomedicine (Lond), 10 (1) (2015), pp. 161-174, 10.2217/nnm.14.178 Epub 2015/01/20PubMed PMID: 25597775 View in ScopusGoogle Scholar [32] C. Hamers-Casterman, T. Atarhouch, S. Muyldermans, G. Robinson, C. Hamers, E.B. Songa, et...
single-domain antibody (sdAb, nanobody) cancer phage display immunoglobulin-like domain immunotherapy programmed death-ligand 1 programmed cell death protein 1 Cluster of differentiation 80 Abbreviations BLI biolayer interferometry CDR complementary determining region PDB Protein Data Bank ...
A novel bispecific nanobody with PD-L1/TIGIT dual immune checkpoint blockade Cancer immunotherapy have changed the paradigm of cancer treatment, but there remains a great need for improvement given that less patients with tumors res... L Ma,J Gai,P Qiao,... - 《Biochemical & Biophysical Resea...
Provided in the present invention are a type of anti-human PD-L1 specific nanobodies and VHH chains thereof, coding sequences of the foregoing nanobodies or VHH chains thereof, corresponding expression vectors and host cells, and a method for producing antibodies.Hong Hoi Ting...