Programmed cell death protein 1,CD279,hPD-1,PDCD1,Programmed Cell Death 1,Systemic Lupus Erythematosus Susceptibility 2,Protein PD-1,PD1,Programmed Cell Death 1 Protein,CD279 Antigen,HPD-L,HSLE1,SLEB2,PD-1,Programmed Cell Death 1 Receptor Recommend Isotype Controls: Anti-HEL-Mouse IgG1 D...
BioXcell InVivoMab anti-mouse PD-1 RMP1-14单克隆抗体与小鼠PD-1(也称为CD279)反应。PD-1是一种50-55kDa的细胞表面受体,由Pdcd1基因编码,属于Ig超家族的CD28家族。PD-1在CD4和CD8胸腺细胞以及活化的T和B淋巴细胞和髓细胞上瞬时表达,在成功消除抗原后PD-1的表达下降。此外,在B细胞前阶段,Pdcd1 mRNA在...
可变结构域序列与原始10F.9G2™克隆号相同,但是恒定区序列已经从大鼠IgG2b变为小鼠IgG1。10F.9G2™-CP001单克隆抗体在Fc片段中也含有D265A突变,使其无法与内源性Fcγ受体结合。 10F.9G2™-CP001单克隆抗体与小鼠PD-L1(程序性死亡配体1,也称为B7-H1或CD274)反应。PD-L1是属于Ig超家族的B7家族的I...
mouse PD1重组蛋白作为抗原,用RPM1-14作为抗体,检测的EC50结合数据。 体内活性 Mice were subcutaneously injected with MC38 (1 × 106) or B16-hCXCR4 (5 × 105). After two weeks, tumors bearing mice were intraperitoneally (ip) treated with murine anti-PD-1 [RMP1–14] (5 mg/kg...
靶点: CD279/PDCD1/PD1 免疫原: Mouse 宿主: Mouse 用途: 仅用于科研 保质期: 1 year 应用范围: FCM 产地: France 标记物: Unconjugate 品牌: AntibodySystem 包装规格: 100ug 抗原来源: Mouse 适应物种: Mouse 克隆性: 是 标识物: Unconjugate 形态: Liquid 保存条件: Use a manua...
mouse PD1重组蛋白作为抗原,用RPM1-14作为抗体,检测的EC50结合数据。 体内活性 小鼠皮下注射MC38(1×106)或B16-hCXCR4(5×105)。两周后,用小鼠抗PD-1[RMP1-14](5 mg/kg,每周两次,持续2周)、Pep R(2 mg/kg,每周5天,持续2周)或两种药物对荷瘤小鼠进行腹膜内(ip)治疗。结果表明,联合治疗,Pep R加...
4. Ngiow, S. F., et al. (2015). 'A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1' Cancer Res 75(18): 3800-3811. 5. Evans, E. E., et al. (2015). 'Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and...
(2015). "A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1" Cancer Res 75(18): 3800-3811 in vivo blocking of PD-1/PD-L signaling Evans, E. E., et al. (2015). "Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into ...
(2015). "A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1" Cancer Res 75(18): 3800-3811 in vivo blocking of PD-1/PD-L signaling Evans, E. E., et al. (2015). "Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into ...
2. Ngiow, S. F., et al. (2015). 'A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1' Cancer Res 75(18): 3800-3811. 3. Rutigliano, J. A., et al. (2014). 'Highly pathological influenza A virus infection is associated with augmented...