PathogenesisAnti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (MDA5-DM) is a subtype of dermatomyositis. Although the aetiology and pathology remain unclear, increasing evidence suggests that viral infection is a potential trigger of MDA5-DM. Multiple factors, ...
Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (MDA5-DM) is a subtype of dermatomyositis. Although the aetiology and pathology remain unclear, increasing evidence suggests that viral infection is a potential trigger of MDA5-DM. Multiple factors, including T...
dermatomyositisinterstitial pneumoniareversible cerebral vasospasm syndromemycophenolate mofetilA 39-year-old woman admitted with multiple joint pain, hand rashes, and shortness of breath was diagnosed with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) with ...
英文摘要: Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis is a subtype of DM characterized by a high propensity for developing interstitial lung disease,particularly rapidly progressive ILD (RPILD).Patients with RPILD often exhibit resistance to corticosteroid and ...
dermatomyositisinterstitial lung diseaseMDA5Anti-melanoma differentiation-associated gene 5 (MDA5) antibody positive dermatomyositis (MDA5-DM) is an autoimmune disease, characterized by a particular skin ulcer and rapidly progressive interstitial lung disease (RP-ILD). This case highlights diagnostic ...
Interstitial lung disease in anti-MDA5 positive dermatomyositis. Clin Rev Allergy Immunol. 2021;60(2):293-304. doi:10.1007/s12016-020-08822-5 PubMedGoogle ScholarCrossref 3. Wang H, Chen X, Du Y, et al. Mortality risk in patients with anti-MDA5 dermatomyo...
Recommendations for the treatment of anti-melanoma differentiation-associated gene 5-positive dermatomyositis-associated rapidly progressive interstitial lung disease Semin. Arthritis Rheum., 50 (4) (2020), pp. 776-790, 10.1016/j.semarthrit.2020.03.007 View PDFView articleView in ScopusGoogle Scholar ...
[摘要] 目的 分析抗黑色素瘤分化相关基因5(MDA5)抗体阳性幼年皮肌炎(JDM)的临床特点及治疗转归。方法 收集首都医科大学附属北京儿童医院风湿科2015年6月至2022年2月收治的487例JDM患儿的临床资料,其中41例(8.42%)为抗MDA5抗体阳性者。对其临床特点、疾病评估、
In this study, we aimed to explore the association between baseline and early changes in the neutrophil-to-lymphocyte ratio (NLR) and the 30-day mortality rate in patients having anti-melanoma differentiation-associated gene 5 (MDA5)-positive dermatomyositis with interstitial lung disease (DM-ILD)...
However, in the present study, we encountered a case of rapidly progressive interstitial lung disease (RP-ILD) complicated by anti-MDA5 antibody-positive dermatomyositis, which developed into respiratory failure due to the re-aggravation of diffuse ground-glass opacity (GGO) during treatment, leading...