To the best of our knowledge this is the first case of Anti-MDA5 Dermatomyositis occurred after BNT162b2 vaccination.D. AstorriL. NalottoE. VaccaroV. CarraroL. BernardiL. PunziC. BernardiAnnals of the Rheumatic Diseases
品牌: abinScience 抗原来源: Human 适应物种: Human 用途: 供科研使用 货号: HV365023 Product Name Anti-Human MDA5/IFIH1 Antibody (ABS1656) Host Species Human Applications ELISA, WB Species Reactivity Human Target MDA5/IFIH1 Accession Q9BYX4 Storage Buffer 0.01M PBS, pH 7.4....
The presence of anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5 Ab) is closely associated with rapidly progressive interstitial lung disease (RP-ILD) in patients with clinically amyopathic dermatomyositis. Despite intensive immunosuppressive therapies, some of these patients still have...
This study identified biomarkers that can be used to assess disease activity and response to therapy in patients with interstitial lung disease complicating anti-melanoma differentiation-associated gene 5 (MDA5) antibody (Ab)-positive clinically amyopathic dermatomyositis (CADM).In 15 patients with int...
Autoimmune PAP (APAP), which accounts for 89% of PAP cases, occurs when anti-GM-CSF antibodies (GMAb) reduce the phagocytic ability of alveolar macrophages, resulting in an inability to process old surfactants in the alveoli and induce surfactant accumulation. The characteristic findings of PAP ...
AB0675 Anti-mda5 positive dermatomyositis: an emerging entityBackground Hypo or amyopathic dermatomyositis (DM) represent about 20% of the classic DM. Melanoma differentiation-associated gene 5 antibody or anti-MDA5 antibody, formerly known as anti-CADM140 antibody, has been reported in the last...
dermatomyositisetanerceptrheumatoid arthritisTNF inhibitorsThe induction of autoimmune diseases during tumour necrosis factor-alpha inhibitor (TNFi) usage has been described. Herein, we report a rare case of a 49-year-old woman with antimelanoma differentiation-associated gene 5 (MDA5) antibody (Ab)-...
Interestingly, a recent study has suggested that rituximab may be a useful therapy for anti-MDA5 Ab (+) ADMs associated with rapidly progressing interstitial lung disease. However, lung infection in this case is the major risk [20]. Gono et al. showed that there is a relationship between ...
clinically amyopathic dermatomyositisinterstitial lung diseaseplasma exchangeClinically amyopathic dermatomyositis (CADM) with anti‐melanoma differentiation‐associated gene 5 (MDA5) antibody (Ab) with rapidly progressive interstitial lung disease (RP‐ILD) is often refractory for intensive immunosuppression....
Plasma exchange (PE) has been reported to be effective for steroid-refractory RP-ILD with anti-MDA5 Ab. However, the timing, frequency, and interval of PE for the treatment of RP-ILD with anti-MDA5 Ab have not yet been established.#We report two cases of RP-ILD with anti-MDA5 Ab ...