Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge.PMID:35731866 Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.PMID:36470928 IL11 activates the placental inflammasome to drive...
Anti-IL-11 antibody therapy decreases levels of IL-11 and pro-inflammatory factors in the lung tissue without shifting the IL-12 – IFN-γ/IL-10 balance.Marina, A. KapinaGalina, S. ShepelkovaVadim, G. AvdeenkoAnna,...
IL-11 plays important roles in hemopoiesis, thrombopoiesis, megakaryocytopoiesis, and bone resorption; It regulates macrophage differentiation and confers mucosal protection after chemotherapy and radiation therapy. Interaction Hematopoietic cells, hepatocytes, adipocytes, neurons, osteoblasts, fibroblasts, ...
TUMOR COMBINATION THERAPY USING ANTI-IL-11 ANTIBODYThe present invention provides a drug combination for treating tumors. The drug combination comprises: an anti-IL-11 antibody or a fragment thereof; and an anti-tumor drug, wherein the anti-tumor drug can cause local IL-11 expression up-...
This was successfully treated with a 2-week triple therapy consisting of lansoprazole, clarithromycin and metronidazole with persistent endoscopic and histological remission. This is a rare case of H . heilmannii -associated acute gastric mucosal lesions, diagnosed by morphology using touch cytology and...
A method for predicting maintenance of response to IL-23 antibody therapy and treating a patient having psoriasis with extended dosing intervals after measuring at least one indicator from psoriasis patients before and during treatment with an IL-23 antibody is useful in the treatment of psoriasis....