Anti-GBM glomerulonephritis or anti-glomerular basement membrane disease/Good Pasture disease is an autoimmune disorder affecting glomerular capillaries resulting in rapidly progressive glomerulonephritis and involvement of pulmonary capillaries manifesting as alveolar hemorrhage. It is considered an immune complex...
ANTI-GBM DISEASE IN ALPORT SYNDROME 10 YEARS LATERdoi:10.1053/j.ajkd.2015.02.219NoneELSEVIERAmerican Journal of Kidney Diseases
“In anti-GBM disease, timely treatment is key to minimizing its potential damage to the kidneys. However, the ultra-rare nature of this condition can delay its identification and diagnosis. Imlifidase, not only reduces antibody lev...
Role of infection and molecular mimicry in the pathogenesis of anti-GBM diseaseGlomerular diseasesdoi:10.1038/s41581-020-0311-8Ellen F. CarneyNature Reviews Nephrology
Conclusions Besides α345(IV) collagen, laminin-521 is another major autoantigen targeted in anti-GBM disease. Autoantibodies to laminin-521 may have the potential to promote lung injury in anti-GBM disease by increasing the total amount of IgG bound to the alveolar basement membranes. 展开 ...
Anti-GBM disease and ANCA during dengue infection. Anti-glomerular basement membrane (GBM) disease is a severe inflammatory renal disorder due to pathogenic autoantibodies directed mainly against the 伪3 ch... KJ Lizarraga,JA Florindez,P Daftarian,... - 《Clinical Nephrology》 被引量: 9发表:...
Canney M, O'Hara PV, McEvoy CM et al (2016) Spatial and temporal clustering of anti-glomerular basement membrane disease. Clin J Am Soc Nephrol 11:1392–1399 3. Casian A, Jayne D (2011) Management of alveolar hemorrhage in lung vasculitides. Semin Respir Crit Care Med 32:335–345 4....
We have compared clinical features and outcomes to those for single-positive AAV and single-positive anti-GBM disease. Because patients with double-positive disease more closely resemble those with single-positive anti-GBM disease at presentation, we have also compared histopathology and treatment in ...
网络抗基底膜型肾小球肾炎 网络释义 1. 抗基底膜型肾小球肾炎 什么意思_英语anti... ... ANTI-GBM DISEASE 抗肾小球基底膜病anti-GBM type glomerulonephritis抗基底膜型肾小球肾炎... dict.youdao.com|基于 1 个网页
These data suggest that increased expression of HB-EGF and erbB4/HER4 is a response to inflammation in the glomerulus in accelerated anti-GBM disease. to determine the potential role of HB-EGF in anti-GBM disease, a blocking monoclonal antibody against HB-EGF (DE10) was administered by ...