Anti-GBM glomerulonephritis or anti-glomerular basement membrane disease/Good Pasture disease is an autoimmune disorder affecting glomerular capillaries resulting in rapidly progressive glomerulonephritis and involvement of pulmonary capillaries manifesting as alveolar hemorrhage. It is considered an immune complex...
Dekervel, M., Fage, N., Vinatier, E.et al.Anti-GBM disease fueled by cardiopulmonary bypass, a lesson for the clinical nephrologist.J Nephrol38, 777–780 (2025). https://doi.org/10.1007/s40620-024-02131-2 Download citation Received27 June 2024 Accepted28 September 2024 Published28 Octobe...
Anti-GBM disease and ANCA during dengue infection. Anti-glomerular basement membrane (GBM) disease is a severe inflammatory renal disorder due to pathogenic autoantibodies directed mainly against the 伪3 ch... KJ Lizarraga,JA Florindez,P Daftarian,... - 《Clinical Nephrology》 被引量: 9发表:...
However, in contrast to anti-GBM disease, ANCA-associated vasculitides are chronic diseases with a high relapse rate. Since morbidity in ANCA-associated vasculitides is dictated by the frequency and severity of relapses, much health benefit would be achieved if a relapse could be prevented or ...
Søren Tulstrup, President and CEO, Hansa Biopharma said, “This is an exciting next step in the development of imlifidase and for patients with anti-GBM disease. GOOD-IDES-02 is the first and currently only pivotal randomized ...
FDA Accepts Investigational New Drug (IND) Application for Phase 3 Study of Imlifidase in Anti-GBM Disease
These data suggest that increased expression of HB-EGF and erbB4/HER4 is a response to inflammation in the glomerulus in accelerated anti-GBM disease. to determine the potential role of HB-EGF in anti-GBM disease, a blocking monoclonal antibody against HB-EGF (DE10) was administered by ...
We had a large series of patients with anti-GBM disease who presented with different renal functions upon diagnosis. They might represent patients at different stages of disease. This large series of patients might cover the entire spectrum of the clinical course of patients with anti-GBM disease...
GFAP在AST/GBM中表达最强,INST、PAM中最弱;S100β在GBM、AST中表达最强,ODG、PAM中最弱。结论结合HE染色、GFAP和S100β的表达结果综合分析胶质瘤的来源及分化程度可较好地诊断胶质瘤的类型。 展开▼ 著录项 来源 《肿瘤药学》 |2015年第3期|189-193|共5页 作者 唐红宇; 梁永; 颜建辉; 刘超; 欧阳松;...
Autoreactivity toward laminin-521 was significantly more common in patients with anti-GBM GN and lung hemorrhage, compared with those with kidney-limited disease (51.5% versus 23.5%, P =0.005). Antilaminin-521 autoantibodies were predominantly of IgG1 and IgG4 subclasses and significantly associated...