Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion. J Thromb Haemost 2010;8:722-729.Reversibility of the anti‐FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion[J] . Journal of Thrombosis ...
Results: When assessed by modified anti-FXa assays in the 96-well format (with an overall 2-fold sample dilution), AnXa dose-dependently reversed the anti-FXa activity of both apixaban and rivaroxaban spiked in plasma. % Reversal increased as a function of the molar ratios (AnXa:inhibitor)...
Edoxaban anti-FXa activity and andexanet effects in vitro.Lu, GenminPine, PollyM. Leeds, JanetDeGuzman, FrancisPratikhya, PratikhyaLin, JoyceMalinowski, JohnHollenbach, Stanley JCurnutte, John TConley, Pamela B
Relationship between anti-FXa activity and thrombin generation.doi:10.1371/JOURNAL.PONE.0116835.G007Thomas OwainL. EmanuelS. KarinTynngrd NahreenSchtt UlfPLOS ONE
The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute a simple solutionIntensive Care Medicine -doi:10.1007/s00134-022-06744-8Johannes.GratzDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, ...
Intensive Care Medicine -doi:10.1007/s00134-022-06768-0Hofmaenner, Daniel A.Singer, MervynSpringer Berlin HeidelbergIntensive care medicine
Hemostatic efficacy and reversal of anti-FXa activity with andexanet were assessed in patients from the ANNEXA-4 study (Andexanet Alfa, a Novel Antidote to the Anticoagulation Effects of FXa Inhibitors) with intracranial hemorrhage (ICrH).Demchuk, Andrew M.Yue, PatrickZotova, ElenaNakamya, ...
Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas. Thromb Res. 2011 in press.Harris LF, Castro-Lopez V, Jenkins PV, O'Donnell JS, Killard AJ. 2011. Comparison of a fluorogenic anti-FXa assay with ...
The effects were much smaller than with rivaroxaban. The use of APTT and/or PT assays to screen the anticoagulant activity of apixaban cannot be recommended. A chromogenic anti-FXa assay can be used for reliable measurements of apixaban concentration.EBSCO_AspJournal of Thrombosis & Haemostasis...
the cha11enge of phannaco1ogica1 thromboprophy1axis in icu patients anti fxa activity does not constitute the simp1e so1ution author s rep1ypatients the pain, cost and any unrecognized harm. The final question is to query whether a LMWH prophylac- tic strategy actually works in the first...