ACT was detected immediately, while AFXa were detected by Factor Xa ELISA kit within 3 months. Data was analysed by different diseases, kinds of LMWH, gender, ages and different renal functions. Results (1) The AFXa and ACT values were significantly higher in the group that received LMWHs ...
Antihemophilic Factor binds factor IXa along with calcium and phospholipid, This complex converts factor X to factor Xa to facilitate clotting cascade. Mechanism of action Antihemophilic factor (AHF) is a protein found in normal plasma which is necessary for clot formation. The administration of AH...
single chain variable fragment sc-dsFv single chain disulfide-stabilized variable fragment fXa factor Xa VEGF human vascular endothelial growth factor PBS phosphate-buffered saline HRP horseradish peroxidase ELISA enzyme-linked immunosorbent assay cfu colony-forming unit CDR complementarity determining region. ...
An in vitro assay was used to measure the level of inhibition of factor X activation by the CDR-grafted TF8-5G9 antibody. In this assay, TF forms an active proteolytic complex with factor VII. This complex then converts factor X to factor Xa by proteolysis. The activated Xa enzymatically...
COMPOSITIONS, KIT AND ONE-STEP METHOD FOR MONITORING COMPOUNDS HAVING ANTI-FACTOR XA AND/OR ANTI FACTOR IIA ACTIVITIESProvided are compositions and methods for accurate determination of the concentration of anticoagulant in a sample such as a blood or plasma sample. The compositions can contain a ...
Compositions, kit and one-step method for monitoring compounds having anti-factor Xa and/or anti factor IIa activitiesProvided are compositions and methods for accurate determination of the concentration of anticoagulant in a sample such as a blood or plasma sample. The compositions can contain a ...
COMPOSITIONS, KIT AND ONE-STEP METHOD FOR MONITORING COMPOUNDS HAVING ANTI-FACTOR Xa AND/OR ANTI FACTOR IIa ACTIVITIESProvided are compositions and methods for accurate determination of the concentration of anticoagulant in a sample such as a blood or plasma sample. The compositions can contain a ...
(factor Xa). Factor Xa forms a complex with factor Va (from the intrinsic coagulation pathway), resulting in the conversion of prothrombin to thrombin, which in turn results in the conversion of fibrinogen to fibrin. In a convenient in vitro functional assay, tissue factor is incubated in the...
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