有关抗生物膜剂（Anti-biofilmAgents）点滴 有关抗⽣物膜剂（Anti-biofilmAgents）点滴 有关抗⽣物膜剂（Anti-biofilm Agents）点滴 ⽣物膜（biofilm）也称为⽣物被膜，是指附着于有⽣命或⽆⽣命物体表⾯被细菌胞外⼤分⼦包裹的有组织的细菌群体。⽣物膜细菌对抗⽣素和宿主免疫防御机制的...
Marine biota is a rich source of biologically active substances with anti-biofilm potential that is scarily studied. The aim of this review is to outline the variety of marine sources delivering antimicrobial agents and their ability to inhibit different stages of the biofilm development, expecting ...
Classification of main microbial enzymes with anti-biofilm activities and their modes of action. This figure categorizes various enzymes known for their ability to disrupt biofilms and outlines their specific mechanisms of action. Enzymes are classified based on their targets within the biofilm matrix, ...
Classification of main microbial enzymes with anti-biofilm activities and their modes of action. This figure categorizes various enzymes known for their ability to disrupt biofilms and outlines their specific mechanisms of action. Enzymes are classified based on their targets within the biofilm matrix, ...
HA-PTs exerted anti-biofilm activity by destroying the integrity of the cell membrane, curbing the motility of single and colonial bacteria, hindering the synthesis of polysaccharide intercellular adhesion, inhibiting the secretion of extracellular DNA, and reducing the metabolic activity of biofilms. ...
The anti-biofilm activity of bacteriocin was evaluated using a microtiter plate method. Quantitative real-time PCR assay evaluated bap gene expression in bacteriocin-treated cells. According to SDS-PAGE, bacteriocin from L. plantarum has a 25-kDa apparent molecular weight. The MICs of bacteriocin ...
The objective of this study was to investigate the anti-biofilm activity of low-molecular weight chitosan hydrogel (LMWCH), a natural biopolymer obtained from the N-deacylation of crustacean chitin, upon clinical relevant Candida species. The in vitro ability of LMWCH to impair biofilm formation ...
Engineered lactobacilli display anti-biofilm and growth suppressing activities againstBiofilms are an emerging target for new therapeutics in the effort to address the continued increase in resistance and tolerance to traditional antimicrobials. In particular, the distinct nature of the biofilm growth state...
Biofilm formation contributes significantly to bacterial drug resistance, and employing enzymes to combat biofilms is an effective way. In this study, UiO-66-NH2 was synthesized to immobilize subtilisin, resulting in enzymatic anti-biofilm composite materials. The stability, biofilm inhibition capabilities...
As for antibiotics15,16, the problem with any long-term treatment strategies is the potential for resistance evolution. We need anti-biofilm strategies, therefore, that also limit the evolution of resistance. One option is to use combinations of therapies, which use multiple drugs to limit resista...