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AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling Bolster, Douglas R, et al (2002) J Biol Chem, 277:23977-80 (2002) Glucose metabolism and cancer Shaw, Reuben J (2006) Curr Opin Cell Biol, 18...
To conclude, BMS-477118 has the potential to activate the AMPK/SIRT1/FOXO3a signaling pathway in inflamed colons. These results suggest that the AMPK/SIRT1/FOXO3a pathway could be a new therapeutic target for UC. Further research is mandatory to explore the therapeutic possib...
研究领域 Signal Transduction Protein Phosphorylation Ser / Thr Kinases Other Kinases Neuroscience Neurology process Metabolism Cardiovascular Lipids / Lipoproteins Fatty Acids Metabolism Cancer Cancer Metabolism Metabolic signaling pathway Integration of energy metabolism Cancer Cancer Metabolism Response to hypoxia ...
Corrigendum to “Dietary Kaempferol exerts anti-obesity effects by inducing the browning of white adipocytes via the AMPK/SIRT1/PGC-1α signaling pathway” [Curr. Res. Food Sci. 8 (2024) 100728] Current Research in Food Science, Volume 10, 2025, Pages 100920 Changyu Xu, Xiaoxi Zhang, Yihua...
HIF-1α is a key factor promoting the development of hepatocellular carcinoma (HCC). As well, AKT-AMPKα-mTOR signaling is a promising target for cancer therapy. Yet, the AKT-AMPKα-mTOR-dependent activation of HIF-1α has not been studied in livers with HCC. In addition, the mechanisms...
High-degree hydrolysis sea cucumber peptides improve exercise performance and exert antifatigue effect via activating the NRF2 and AMPK signaling pathways in mice 2021, Journal of Functional Foods Show abstract Natural bioactive peptides to beat exercise-induced fatigue: A review 2021, Food Bioscience ...
It has been reported that alkaloids derived from Coptis chinensis exert anti-adipogenic activity on 3T3-L1 adipocytes by downregulating peroxisome proliferation-activity receptor-γ (PPAR-γ) and CCAAT/enhancer binding protein-α (C/EBP-α). However, the signaling-based mechanism of the inhibitory ...
cascade bioscience | cayman | cayman chemical | CDN | cedarlane | cedarlanelabs | celartia | celex | cell biolabs | cell marque | Cell Point Scientific | cell projects | cell sciences | cell signaling | cell signaling technology | Cell Signaling Technology (CST) | Cell Signaling Technology, ...
Phloroglucinol possesses anti-inflammatory activities by regulating AMPK/Nrf2/HO-1 signaling pathway in LPS-stimulated RAW264.7 murine macrophagesPhloroglucinolHO-1anti-inflammatoryRAW2647 macrophageLPSNF-KAPPA-BACTIVATED PROTEIN-KINASENITRIC-OXIDE SYNTHASE...