本文主要介绍的是英语缩写词"Anti-TNF",它实际上代表的是"Anti-tumor necrosis factor drugs",中文翻译为"抗肿瘤坏死因子药物"。这一缩写在医学领域中被广泛使用,特别是在处方药物的标识中,用于简洁地表示其功能。"Anti-TNF"的中文拼音是"kàng zhǒng liú huài sǐ yīn zǐ yào wù",它被...
successes with infliximab, considered by many to be a therapeutic breakthrough in the management of Crohns disease, has sparked a search for additional biologic agents.The focus of one area of research has been the development of humanized monoclonal antibodies to tumor necrosis factor-alpha (TNF-...
Anti TNF drugs are established therapy in rheumatoid arthritis with some restrictions according national recommendations. Stopping therapy for short periods does not necessarily lead to flares. Recently, it has been demonstrated that combination therapy with methotrexate and infliximab can be tapered and di...
a phase 3 study, the investigators wanted to determine the efficacy and safety of rituximab in the treatment of patients with rheumatoid arthritis for whom anti-TNF-alpha therapy had been inadequate. They were interested in rituximab because it has a different mechanism of action from the anti-...
Biologic therapy involving anti-tumor necrosis factor-α (anti-TNFα) agents has fundamentally changed the management of patients with immune-media
"We might be able to use three different TNF-alpha inhibitors," (infliximab, etanercept, and the investigational drug adalimumab [D2E7]) she said. Dr. Hansen recommends that physicians try this approach in their patients. "Importantly, side effects appeared to be no different in patients who ...
Trotta F, Valentini G. Safety of anti-TNFα biological drugs. Reumatismo 2005; 57 (Suppl. 1):34-39.Trotta F,Valentini G.Safety of anti-TNFalpha biological drugs. Reumatizam . 2005Trotta, F., and Valentini, G. (2005). Safety of anti-TNFalpha biological drugs. Reumatismo 57, 34-39. ...
Anti-TNF-α drugs for refractory inflammatory bowel disease: Clinical- and cost-effectiveness analyses. Ottawa: Canadian Agency for Drugs and Technologies in Health;; 2009.Anti-TNF-α drugs for refractory inflammatory bowel disease: Clinical- and cost-effectiveness analyses. Asassi N,Black...
Soluble TNF receptor–Fc fusion protein (etanercept) TNF antagonism insulin secretion ↑, FBG ↓, CRP ↓, LDL ↓, adiponectin ↑, no effect on sensitivity of insulin Common side effects may include injection site reactions, infections, and headaches. [99] Infliximab TNF antagonism Fasting glucose...
Paradoxical psoriasiform reactions to anti-tumor necrosis factor α (TNFα) agents have been described. We aimed to study the association between these reactions and polymorphisms in genes previously associated with psoriasis or other autoimmune diseases. A total of 161 patients with plaque-type psoria...