Autoantibodies to the NMDA receptor have recently been described as a cause of encephalitis in children. Clinical presentation and radiological findings may resemble those of demyelinating disorders and create challenges for early recognition by providers. Here we discuss the features of anti-NMDA ...
Overlap syndromes of anti-NMDA receptor encephalitis and MOG-mediated demyelination have been reported. In this case we provide a long-term longitudinal follow-up of clinical and imaging characteristics as well as of antibody dynamics. Case presentation We report a 32-year-old male patient who pres...
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a severe but treatable autoimmune disorder which diagnosis depends on sensitive and specific anti... N Gresa-Arribas,MJ Titulaer,A Torrents,... - 《Lancet Neurology》 被引量: 389发表: 2014年 Anti-NMDA Receptor Encephalitis Antibody Bin...
Anti-NMDA-receptor encephalitis: A reviewAnti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis, often mistaken for viral infection, presents a bewildering mix of behavioral, psychiatric, movement, speech, autonomic,...
It is frequently found in young women and associated with an underlying teratoma. Although rare, this diagnosis should be considered in young females for whom a rapid onset of encephalitis cannot be explained by more common causes. 展开 关键词: Anti-NMDA MRI NMDA receptor encephalitis teratoma ...
this immune response is self-limited, because even for patients without tumors, antibody titers gradually decline, correlating with gradual cognitive improvement.24 Despite several advances in our understanding of the NMDA-R and clinical manifestations of its associated encephalitis, ...
Finally, accessible tools need to be developed that allow for reliable identification of specific antibody markers against synaptic proteins. 展开 关键词: Neuroautoimmune disease Anti-NMDA receptor Encephalitis Seizures Psychosis Cell based assay
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an anti-neuronal antibody-mediated inflammatory brain disease that causes severe psychiatric and neurological deficits in previously healthy patients. The aims of this study were to demonstrate the clinical characteristics of patients diagnosed with...
Frechette ES, Zhou L, Galetta SL, Chen L, Dalmau J: Prolonged follow-up and CSF antibody titers in a patient with anti-NMDA receptor encephalitis. Neurology. 2011, 76: S64-66. 10.1212/WNL.0b013e31820c34de. Article PubMed Google Scholar Alexopoulos H, Kosmidis ML, Dalmau J, Dalakas...
Anti-NMDA receptor encephalitis is an immune-mediated disorder associated with IgG antibodies to the GluN1 subunit of the NMDA receptor.1 The antibody reactivity depends on the conformation of GluN1 and it is detectable by use of immunohistochemistry of rat brain, cultures of dissociated rat hippoca...