96,112CD155 has the highest affinity to TIGIT and lower affinity to CD96 and CD226. CD112 binds TIGIT and CD226 less strong than CD155, and does not bind CD96.96,112CD111 only interacts with and stabilizes CD155.113Nectin-4 only interacts with TIGIT...
The decrease in leptin and resistin and the increase in adipo- nectin in LFE-treated mice, together with reduced triglycerides and glucose level in plasma, strongly support the anti-obesity effects of LFE in HFD-fed mice. Discussion Although L. foenum-graecum has been used as an oriental ...
Nectin-4-targeted immunoSPECT/CT imaging and photothermal therapy of triple-negative breast cancer. PMID: 35614462 Antibody-based in vivo leukocyte label for two-photon brain imaging in mice. PMID: 35637871 In vivo application of mAb directed against the gammadelta TCR does not deplete but generate...
The terms “CTLA-4,”“CTLA-4 protein,” and “CTLA-4 antigen” are used interchangeably herein to refer to human CTLA-4, or any variants (e.g., splice variants and allelic variants), isoforms, and species homologs of human CTLA-4 that are naturally expressed by cells, or that are ex...
On the other hand, junctional proteins at the germ cell side tend to decrease (e.g., nectin-3, afadin, and lamininγ3) (Lee et al. 2004; Siu and Cheng 2004) following adjudin treatment. We speculate that following adjudin administration, Sertoli cells respond by expressing more junctional ...
Cytochalasin D K562, HCT-116, and Hep-G2 Enhances NK cell IFN-γ production and cytotoxic activity; induction of NKG2D, DNAM1, and NKp30 expression on NK cells Induction of ULBPs, MICA, PVR, Nectin-2 and B7-H6 [86] Nocodazole No effect on NK cell functions; induction of NKG2D, DNA...
The structure and activities of echinonectin: a developmentally regulated cell adhesion glycoprotein with galactose-specific lectin activity. PMID: 1794037 Possible functions of a new genetic marker in central nervous system: the sulfated glycoprotein-2 (SGP-2). PMID: 1626310 ...
Preparation of retroviral supernatant and transduction were performed as previously described.14Briefly, T-cells were incubated with retroviral supernatant in the presence of RetroNectin (Takara, Kusatsu, Japan) at 37° C. Retroviral supernatant was replaced with freshly harvested supernatant every 12 hou...
Although chimeric antigen receptor (CAR) T cells are effective against B-lineage malignancies, post-CAR relapse is common, and efficacy in other tumors is limited. These challenges may be addressed through rational manipulations to control CAR T cell fun
The aim of this study is to elucidate against Tb-RI, Tb-RII, CTGF, aI(I) procollagen, fibro- the mechanisms of the antifibrogenic effect of EGCG nectin or a-SMA, and secondary antibodies con- in activated HSC. We hypothesize that the anti- jugated with horseradish peroxidase (Santa Cruz...