Introduction: The new COVID-19 infection is a global problem. In Russia, the 10th version of temporary clinical guidelines allows intravenous administration of anti-IL6 drugs. The aim was to evaluate the effect of anti-IL6 drugs when administered intravenously. Material and methods. 122 patients...
Cardio-and Neurotoxicity of Selected Anti-COVID-19 Drugs. Pharmaceuticals. 2022, 15(6): 7653.Stauber T, Moschini G, Hussien A A, et al.IL-6 SIGNALING EXACERBATES HALLMARKS OF CHRONIC TENDON DISEASE BY STIMULATING PROGENITOR PROLIFERATION & MIGRATION TO DAMAGE.bioRxiv.2023: 2023.02. 13.528273....
The armamentarium for the treatment of dyslipidemia today comprises six different modes of action with overall around 24 different drugs. The treatment of lipid disorders was revolutionized with the introduction of statins which have become the most important therapeutic option available today to reduce ...
Drugs used for the prevention and treatment of allergic diseases are called as antiallergic agents. Such kinds of drugs include: 1. anti-histamine drug which mainly includes histamine H1 receptor antagonists, such as promethazine, diphenhydramine, etc., it can compete with histamine to bind to...
One can note from the Table 4 that the selected drugs change with mutations. Baloxavir marboxil was not selected even once for the reference sequence from December 2019, but has been selected by two methods for the February isolate. A recent pre-print29 reports the results of this antiviral...
The secretally: immunostimulation by anticancer drugs. Nat. Rev. Drug Discov. 11, 215–233 (2012). CAS PubMed Google Scholar Mikyskova, R. et al. Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in...
Postoperative pain relief is crucial for full recovery. With the ongoing opioid epidemic and the insufficient effect of acetaminophen on severe pain; non-steroidal anti-inflammatory drugs (NSAIDs) are heavily used to alleviate this pain. However, NSAIDs
Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic implants, systemic lupus er
The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for IL-6. Another embodiment of this invention relate
An anti-IL6 agent that blocks binding of IL-6 to IL-6 receptor, for example, an anti-IL6 antibody comprising a heavy chain variable region of SEQ ID NO:99 and a light chain variable region of SEQ ID NO:97, is useful in the treatment or prevention of infection of a human with SARS...