本公司经销Acetyl-Histone H4(K12),乙酰化组蛋白H4抗体,克隆类型为polyclonal,宿主来源是Rabbit,Acetyl-Histone H4(K12)乙酰化组蛋白H4抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!货号:BY-3746R英文名称:Anti-Acetyl-Histone H4(K12)中文名称:乙酰化组蛋白H4抗体其他名称:名H4F2; H4FN; HIST1H4; ...
By using as immunogen a highly abundant and universal eukaryotic nuclear protein (histone H4) modified in a manner not typical of secreted proteins (acetylation of lysine side chains), antiserum has been raised in rabbits having the single amino acid 系- N-acetyl lysine as the recognition ...
be used to identifythehistonemodification site within the general promoter region, as well as the kineticsofhistonemodification at that site (Fig 5B). labome.com labome.com 另外,这种方法可以用来确定通用启动子区域内的组蛋白修饰位点,以及组蛋白某个位点的修饰动力学(图5B )。
More than 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, ...
and lysine isonicotinylation in vitro. Intriguingly, when we analysed the structures of the three isomers, we found that the structure of Kinicis similar to INH. Therefore, we wanted to characterise Kinicbased on histone modification. To identify this PTM on histones, a customer-designed pan ...
A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects...
Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but ...
3b), suggesting that CD40 signaling promotes pro-inflammatory activation by regulating histone modification with FAO-derived acetyl-CoA. To further investigate this, we applied CRIPSR-based gene ablation in BMDMs as described above. In control BMDMs, FGK45 treatment increased histone H3 (H3ac) and...
免疫原 A synthetic peptide corresponding to a sequence containing Pan Lactic acid-Lysine. 靶点背景信息 Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages. In M1 macrophages, lactic acid is derived from incompletely oxidized glucose and...
The other two are histone tail modifications and microRNA regulation of mRNA. We have previously written about histone tail modification in several of our blogs. See for example (ref), (ref), (ref), and (ref). A few items in this current blog entry are also concerned with these other ...