These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 ...
使用Company C 和TransGen产品,检测HeLa细胞中内源性Histone H3的定位。细胞采用多聚甲醛固定,0.3% Triton X-100 透膜,一抗4℃孵育过夜,Phalloidin用于标记F-actin(红色),Hoechst用于标记细胞核 (蓝色)。结果显示,Histone H3主要定位在细胞核上 (绿色),与Company C 产品相比,TransGen产品的免疫荧光强度较强,定位清...
These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 ...
上海康朗生物科技有限公司主要致力于“Anti-Histone H3/HIST3H3抗体”的生产销售。多年的“Anti-Histone H3/HIST3H3抗体”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深受广大用户信赖。欢迎来电咨询或前来选购。 联系电话:021-6199820
Sequence similaritiesBelongs to the histone H3 family. Developmental stageExpressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Post-translational modificationsAcetylation is generally linked to gene activation. Acetylation on Lys-10 (...
Goodarzi M, Correa AM, Ajani Jaffer, Swisher SG, Hofstetter WL, Guha Sushovan, Deavers MT, Rashid Asif and Maru DM: Anti-phosphorylated histone H3 expression in Barrett's esophagus, low-grade dysplasia, high-grade dysplasia, and adenocarcinoma. Modern Pathol 22: 1612-1621, 2009....
组蛋白H3 (Histone H3)是细胞核小体的重要组成部分,其与H2A、H2B和H4共同组成一个异八聚体,DNA紧密缠绕其上,形成一个核小体结构。Histone H3在细胞增殖、转录调节、DNA的修复及复制以及维持染色体的稳定性等方面具有重要作用。多种翻译后修饰对Histone H3功能的改变起到了重要的作用,Histone H3 Ser10及Ser28的...
ProductnameAnti-HistoneH3(citrullineR2+R8+R17)antibody-ChIPGrade DescriptionRabbitpolyclonaltoHistoneH3(citrullineR2+R8+R17)-ChIPGrade Specificityab5103detectsa17kDabandinsinglelaneWesternBlot.PeptideinhibitioninWesternBlot hasn'tbeenprocessed.ModificationspecificityisdeterminedbyPeptideArray.ab5103binds stronglytoHis...
expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. ...
setofpost-translationalmodificationsofhistones,alsocalledhistonecode,andnucleosomeremodeling. SequencesimilaritiesBelongstothehistoneH3family. DevelopmentalstageExpressedduringSphase,thenexpressionstronglydecreasesascelldivisionslowsdownduringtheprocessof differentiation. ...