靶点全称 H2A.X variant histone 靶点别名 H2A.X; H2A/X; H2AFX 靶点研究领域 Epigenetics and Nuclear Signaling 亚型 IgG2a Sample Application Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-2: 3T3 cell lysates untreated and treated with Hydroxyurea, Primary antibody: D190788(H2AX(Phospho-Ser139...
属性 保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol 运输条件 2-8°C 靶点Uniprot 登记号 P04908 靶点基因 ID 8335 靶点全称 H2A clustered histone 4 靶点别名 H2A/m; H2AFM; HIST1H2AB 靶点研究领域 Epigenetics and Nuclear Signaling 亚型 Immunogen-specific rabbit IgG 相关...
ChIP - Histone H3 (acetyl K9) antibody [AH3-120] (ab12179) Chromatin was prepared from Hela cells according to the Abcam X-ChIP protocol. Cells were fixed with formaldehyde for 10min. The ChIP was performed with 25µg of chromatin, 5µg of ab12179 (blue), and 20µl of Protein...
Post-translational epigenetic modification of histones is controlled by a number of histone-modifying enzymes. Such modification regulates the accessibility of DNA and the subsequent expression or silencing of a gene. Human histone methyltransferases (HM
epigeneticsreactive oxygen speciesSUV39H1Epigenetic deregulation is involved in acute myeloid leukemia (AML) pathogenesis and epigenetic targeting drugs are in clinical trial. Since the first results with histone-deacetylase inhibitors in AML are controversial, novel single and combined treatments need to ...
Postberg J, Jönsson F, Weil PP, Bulic A, Juranek SA, Lipps HJ. 27nt-RNAs guide histone variant deposition via 'RNA-induced DNA replication interference' and thus transmit parental genome partitioning in Stylonychia. Epigenetics Chromatin. 2018 Jun 12;11(1):31.View Article ...
58 This approach has been exploited to combine multiple activator domains derived from epigenetic enzymes, such as the catalytic domain of DNA demethylases (e.g., TET159,60) or histone acetyltransferases (e.g., p30061), to generate high levels of gene activation. Alternatively, repetitive ...
Post-translational epigenetic modification of histones is controlled by a number of histone-modifying enzymes. Such modification regulates the accessibility of DNA and the subsequent expression or silencing of a gene. Human histone methyltransferases (HM
dendritic cell epigenetics HDAC ATAC-seq Cut&Run pDC cDC1 cDC2 tumor immunity IRF Research topic(s) CP: Cancer CP: Immunology Introduction Dendritic cells (DCs) are important players in the body’s immune response and orchestrate tumor immune surveillance by bridging the innate to the adaptive im...
运输条件 2-8°C 靶点Uniprot 登记号 P06400 靶点基因 ID 5925 靶点全称 retinoblastoma 1 (Phospho-Ser795) 靶点别名 RB; pRb; OSRC; pp110; p105-Rb 靶点研究领域 Epigenetics and Nuclear Signaling, Cancer 亚型 Immunogen-specific rabbit IgG 相关...