Objective: To describe an oligosymptomatic case of anti-GABA A receptor encephalitis.Background: The antibodies against GABA A receptor are associated with a variety of severe neurological features, form status epilepticus to progressive encephalopathies. Sixty percent of the patients harbor a neoplasia...
Cronin C, Edmiston K, Griffin T (1991) Hematologic safety of choline magnesium trisalicylate: a nonopioid analgesic. J Pain Sympt Man 6:158 ArticleGoogle Scholar 18 Literatur Antognini JF (1993) Intrathecal acetylsalicylic acid and indomethacin are not analgesic for a supramaximal stimulus. Anesth ...
P.1.c.023 GABA-A receptor-mediated neurotransmission in ventromedial hypothalamus modulates fear and antinociceptionDysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome in humans. Furthermore, several studies have implicated the hypothalamus in the elaboration of pain ...
of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3). [provided by RefSeq, Nov 2009...
The term “Ophelia syndrome” was first used by Carr in 1982 to describe the limbic encephalitis in his daughter associated with Hodgkin’s lymphoma [1]. It was until 2011 that the metabolic glutamate receptor5 (mGluR5) antibody was finally identified in this syndrome in two patients [2]. ...
GABA A receptor agonist Zonisamide-bupropion slow-release [Empatic] Na channel modulators; carbonic anhydrase inhibitor/DA and SE transmission modulator Obesity NCT00709371, NCT00339014 Canagliflozin/phentermine SGLT-2 inhibitor/noradrenergic agonist Obesity NCT02243202 Dapagliflozin/exenatide SGLT 1/2 ...
We then investigated whether augmenting GABAergic transmission could ameliorate anxiety-like behavior provoked by AMPK deletion. Thirty minutes after an acute injection of muscimol (5 mg/kg, i.p.), a GABAA receptor agonist [46], into AMPK KOmPFC mice, we conducted a behavioral test. Our res...
Initially, we conducted a transcriptomic analysis of 70 SLE patients and used clustering gene expression data to divide samples into two clusters, one of which had a significantly larger proportion of patients with neuropsychiatric syndrome. Subsequently, weighted gene co-expression network analysis (...
Alogabat may be considered a precision therapy for this DEE, because the genes partially lost in Angelman syndrome include those coding for the α5 subunit of GABAA receptors; alogabat helps the remaining α5 subunits to perform their function. Another interesting group of GABAA receptor PAMs ...
[52]—compatible with a putative role of AMH in the neuroendocrine defects of PCOS. Another series of mouse experiments suggested that maternal AMH excess produces a PCOS-like syndrome in female progeny, including increases in GABAergic appositions onto GnRH neurons, GnRH neuron firing rate, LH ...