Antiendothelial cell antibodies (AECA) are a family of autoantibodies able to react with endothelial cells (EC), which differ from each other for antigen specificity, ability to bind to surface or intracellular structures, and functional effects. Natural AECA exist, display invitro anti-inflammatory...
antiendothelial cell antibodiesantineutrophil cytoplasmic antibodiescrescentic glomerulonephritispauci-immunevasculitisSUMMARY:Aim:聽 Pauci-immune crescentic glomerulonephritis (CrGN) is frequently associated with circulating anti-neutrophil cytoplasmic antibodies (ANCA). However, in patients with ANCA-negative pauci-...
血清抗血管内皮细胞抗体(anti-endothelial cell autoantibodies,AECA)水平的变化,与系统性红斑狼疮的复发与缓解有一定的关系。 2. Objective To discuss the value of detection of serum serum anti-nuotrophil cytoplasmic autoantibodies(ANCA) and anti-vascular endothelial cell antibodies(AECA) in the diagnosis of...
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Anti-endothelial cell antibodies (AECA) are circulating antibodies that bind to endothelial antigens and induce endothelial cell damage. AECA have been detected in patients with collagen vascular disease (CVD) and their presence is associated with interstitial lung disease (ILD) in cases of CVD. How...
Anti-endothelial cell antibodies (AECA) are detectable in a heterogenous group of autoimmune and inflammatory conditions. These antibodies have also been detected in healthy individuals. Nevertheless, most of the literature focuses on AECA in pathological conditions and their targets and functions in heal...
BACKGROUND AND OBJECTIVES : Anti-endothelial cell antibodies (AECA) are found in the sera of many patients with Kawasaki disease (KD). In this study, the pathogenic role of AECA in the development of coronary arterial lesions of KD was investigated. SUBJECTS AND METHODS : Serum IgM-AECA conce...
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In addition, anti-endothelial cell antibodies targeting antigens such as vinculin have been detected in SSc patients with and without PAH [11]. Vinculin overexpression in SSc may produce anti-vinculin antibodies, which may cause vascu- lopathic symptoms. According to Suliman and colleagues, PAH ...
Some have hypothesized that perhaps anti-endothelial cell antibodies, which are present in the circulation in several autoimmune conditions, may be responsible for the injury. Several studies have correlated the presence of anti-endothelial cell antibodies with the development and severity of IPF (Magro...