Changes in Leukocyte Subsets And Anti-dsDNA Antibody Levels After B Cell Depletion Therapy in Systemic Lupus ErythematosusMark Lazarus
Anti-dsDNA antibody is one of the important marker autoantibodies in lupus. • Presence of anti-dsDNA reactivity is not always associated with lupus nephritis. • Cross-reactivity of anti-dsDNA antibodies with different cellular antigens seems to be an important criterion for their pathogenic pote...
Anti-5S RNA/protein (RNP) antibody levels correlate with disease activity in a patient with systemic lupus erythematosus (SLE) nephritisdoi:10.1111/j.1365-2249.1994.tb07008.xsystemiclupuserythematosusnephritisautoantibodies5SRNA/proteincomplexSUMMARYA patienl with systemic lupus erythematiosus (SLE) and...
Bizzaro N, Villalta D, Giavarina D, Tozzoli R (2012) Are anti-nucleosome antibodies a better diagnostic marker than anti-dsDNA antibodies for systemic lupus erythematosus? A systematic review and a study of metanalysis. Autoimmun Rev 12:97–106. doi:10.1016/j.autrev.2012.07.002 Article CAS...
anti-dsDNA-antibodiesSystemic lupus erythematosus (SLE) is associated with a high risk of venous and arterial thrombosis, not necessarily associated with prothrombotic antiphospholipid antibodies (Abs). Alternatively, thrombosis may be due to an increased titer of anti-dsDNA Abs that presumably promote ...
A patienl with systemic lupus erythematiosus (SLE) and nephritis without antibodies to dsDNA but with antibodies lo a 5S RNA/protcin (RNP) complex is presented. Combined RNA precipitation and Western blotting experiments strongly suggested that these newly Identified autoantibodics recognized a disti...
Comparative analysis of contemporary anti-double stranded DNA antibody assays for systemic lupus erythematosus Objective: Elevated double-stranded DNA (dsDNA) antibody levels in blood serum are considered a disease-specific marker in systemic lupus erythematosus (SL... CJ Bauer,P Karakostas,N Weber,.....
Lupus, 19 (8) (2010), pp. 906-912 Crossref View in Scopus Google Scholar [33] T.R. Chiaro, K.W. Davis, A. Wilson, B. Suh-Lailam, A.E. Tebo Significant differences in the analytic concordance between anti-dsDNA IgG antibody assays for the diagnosis of systemic lupus erythematosus—...
Objectives. The anti-dsDNA antibodies are a marker for Systemic Lupus Erythematosus (SLE) and 70–98% of patients test positive. We evaluated the demographic, clinical, laboratory, and therapeutical f...
14/31 (45.2%) SLE anti-dsDNA negative patients were found to be anti-NCS antibody positive. Table 2. Laboratory investigations of the systemic lupus erythematosus patients according to anti-nucleosome antibody positivity. Laboratory findingsMedian (range) or n (%)Group A(n = 48)Group B(n = ...