Anti-dsDNA antibodiesare listed as an immunologic criterion for the classification of SLE by theACR. In a large prospective study, the combination of an elevated titer of anti-dsDNA and low-serum C3 has a high positive predictive value for the diagnosis of SLE.13 ...
anti-dsDNA antibodiesAnalysis of somatic mutations revealed that induction of anti-dsDNA autoantibodies from SLE patients are antigen driven and thus T cell dependent. Since DNA per se has repeatedly been shown not to be immunogenic, various mechanisms leading to the production of anti-dsDNA-...
抗体名: Anti-dsDNA Antibody (3E10#) 亚型: IgG2a, kappa 浓度: 1 mg/ml % 是否单克隆: 是 免疫原: NA 宿主: Mouse 用途: 仅用于科研 保质期: 1 year 应用范围: ELISA,IF,Dot 产地: France 标记物: Unconjugate 品牌: AntibodySystem 包装规格: 100ug 抗原来源: NA 克隆性: ...
牛抗双链DNA抗体;天然DNA抗体检测试剂盒dsDNAAnti-double-stranded DNA antibodies010 牛β-酪啡肽检测试剂盒β-cmβ-casomorphin5160umol/L1 Anti-dsDNA 试剂盒多少钱牛纤维蛋白原检测试剂盒FbgFibrinogen3.125100μg/ml0.1 牛腺苷酸活化蛋白激酶检测试剂盒AMPKadenosine monophosphate activated protein kinase7.5240ng/mL1...
buffer. The density of the yellow coloration is directly proportional to the amount of captured dsDNA-specific antibodies in the plate. The light absorbance (OD value) under 450nm wavelength of the wells is determined using a microplate reader. The antibody ...
Provided herein are antibodies for determining the concentration of anti-dsDNA and anti-chromatin antibodies in biological samples. Inventors: Walker, Roger (Benicia, CA, US) Breneman III, John Wesley (Brentwood, CA, US) Application Number: 14/019150 Publication...
In 2 radioimmunoassays in use to detect antibodies to dsDNA, the Farr assay and the PEG assay, we observed inhibitory effects of normal human serum (NHS) on the DNA binding by SLE sera. This was found to be due by the fact that, during incubation at 37°C, CO2, introduced in the in...
High avidity anti-dsDNA antibodies are more specific for SLE diagnosis, and more closely associated with renal involvement than intermediate or low-affinity anti-dsDNA antibodies. ELISA methods are largely used to detect anti-dsDNA, but their high sensitivity is inversely related to specificity because...
difference in enrichment between autoantibodies against RNA- and DNA-associated autoantigens in isolated SLE CIC, suggesting that the RNA-associated autoantibodies are more prone to form complexes in the circulation in SLE, in contrast to antibodies against DNA-associated autoantigens including dsDNA. ...
genetic and hormonal in nature.1 The induction of T cells with regulatory and suppres- sive capacity has been suggested as a novel therapy to control the activities of pathogenic T cells and Th-cell- mediated B-cell production of antibodies responsible for disease.2–4 The inhibitory capacity ...