Compound 4i induced alteration of cell cycle checkpoint proteins and induced DNA dam- age. We investigated the effects of 4i on the expression of proteins involved in regulation of the cell cycle and in spindle assembly. Cyclin B1 is involved in the G2 to M transition as a complex ...
In the present study, drug treatment in HCT-8 cells resulted in down-regulation of CDK2 protein levels and up-regulation of the levels of the cell cycle regulator p21. The increased levels of p21 protein expression may inhibit the formation of the cyclin A-CDK2 complex and contribute to ...
An application of the cell cycle regulatory protein Cyclin B1 in preparing the medicines for preventing and treating the infestation and transfer of human esophagus cancer is disclosed.詹启敏宋咏梅黄振赵春玲薛丽燕吕宁陈阿梅付明董立佳
人扁桃体上皮细胞Cyclin Antibody Sampler Kit 人口腔角质细胞Cell Cycle Regulation Antibody Sampler Kit II 人牙龈成纤维细胞HER2/ErbB2 (29D8) Rabbit mAb (PE Conjugate) Anti-biotin, HRP-linked Antibody(2E)-3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acidUTEX 36 [CCAP...
The greatest growth inhibition was observed in MDA-MB-468 where the sub-G0/G1 apoptotic population was significantly increased with a concomitant cyclin D1 suppression and p21 upregulation in these three cell lines [25]. In addition, Mekuria AN et al.’ study further showed that lycopene ...
Figure 3D shows the expression of cellular proteins related to proliferation, cell cycle, β-catenin, and cyclin D1. The expression of these proteins was reduced by adding rbNPs but not by rb-sup. In contrast, no significant change in β-catenin expression was observed after the addition of...
In that study, elevated ROS upregulated the cyclin-dependent kinase inhibitor, p16INK4A/Rb, which resulted in defective stem cell function. Based on those data, AM was thought to be essential for autonomous regulation of HSCs in the murine fetal liver through its effects on intracellular iron ...
Regulation of nuclear pre-mRNA domain-containing protein 1A, p15INK4B-related protein, Cyclin-dependent kinase inhibitor 2B-related protein, RPRD1A, P15RS Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industr...
(P-TEFb). A transcriptional co-activation complex comprising cyclin-dependent kinase 9 (CDK9) and cyclin T1, which phosphorylates RNA polymerase II to release it from the pause-release checkpoint and stimulate transcriptional elongation. Super-enhancers Large cis-regulatory elements comprising clusters ...
Breast cancer is the most common malignant tumor and one of the leading causes of cancer-related death in women throughout the world. This study is a parallel, randomized, double-blind, controlled, 12-week supplementation trial, investigating the anti-inflammatory effects of dietary intake of fish...