Activity of IMMU-130 anti-CEACAM5-SN-38 antibody-drug conjugate (ADC) on metastatic colorectal cancer (mCRC) having relapsed after CPT-11: Phase I study. Paper presented at: 2014 Annual Meeting of the American Society of Clinical Oncology; Chicago, IL. 56. Starodub A, Ocean AJ, G...
proliferation, and survival of T cells (right panel). Likewise, by upregulating the expression of receptors and ligands, inter-relationships also exist between co-stimulatory molecules such as CD28 and CD40. Another strategy using agonistic antibodies is modifying the ...