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It is often used to treat depression and anxiety; however, it can decrease the efficacy of certain anticancer drugs and antineoplastic drugs as a result of hyperforin (active compound in St. John’s wort) inducing the CYP3A4 enzyme system and P-glycoprotein drug transporter which subsequently ...
Depression: Treatment Left untreated, major depression can set off a chain of social, emotional and health consequences that add to patients' overall stress, which can include alcohol or drug abuse, anxiety, social isolation, relationship conflicts, work or school difficulties or suicide. A 2019 re...