Journal of Cancer MoleculesWu H-C, Huang C-T, Chang D-K (2008) Anti-angiogenic therapeutic drugs for treatment of human cancer. J Cancer Mol 4: 37-45Wu H-C, Huang CT, Chang DK (2008) Anti-angiogenic therapeutic drugs for treatment of human cancer. J Cancer Mol 4: 37-45....
Anti-angiogenesistreatment is a promising new form of cancer therapy. Specially-designed medications inhibit the growth of newblood vesselsinside and leading to canceroustumors. Without a steady blood supply, tumors stop growing and manycancer cellswithin the mass eventually die. Several different types...
In 1971, Dr. Judah Folkman first proposed the hypothesis that tumor growth is angiogenesis dependent [1]. Angiogenesis, the growth of new capillary blood vessels from preexisting vasculature, has long been appreciated for its role in normal growth and development and now is widely recognized for ...
ANTI-ANGIOGENESIS THERAPY FOR TREATMENT OF OVARIAN CANCERPROBLEM TO BE SOLVED: To provide a method of effectively extending progression free survival of a patient diagnosed with ovarian cancer in which administration of a chemotherapeutically effective amount of an anti-VEGF antibody is continued....
115lung cancer,116gastric cancer (GC),117cervical cancer (CC),118and other malignant tumors.118,119Both angiogenesis and lymphangiogenesis are essential to metastatic tumors.39,49VEGF-C,-D/VEGFR-3 is the primary signal pathway mediates lymphangiogenesis.120Blocking VEGF-C,-D/VEGFR-3 pathway has ...
Recent strategies for the treatment of cancer, other than just tumor cell killing have been under intensive development, such as anti-angiogenic therapeutic approach. Angiogenesis inhibition is an important strategy for the treatment of solid tumors, which basically depends on cutting off the blood sup...
We discuss vasculogenic mimicry of solid tumors and describe strategies for identifying putative tumor vascular targets. We end by discussing the future prospects for the clinical use of vascular targeting in treatment of cancer. 展开 关键词: angiogenesis anti-angiogenic therapy vasculogenic mimicry ...
Angiogenesis is one of the hallmarks of cancer and a crucial requisite in the development of tumors. Interrupting this process by blocking the vascular endothelial growth factor (VEGF) with the monoclonal antibody bevacizumab has been considered a possible breakthrough in the treatment of various types...
Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Nat Rev Cancer. 2007;7(6):475-485. doi:10.1038/nrc2152 PubMedGoogle ScholarCrossref 6. Maumus-Robert S, Berard X, Mansiaux Y, Tubert-Bitter P, Debette S, Pariente A. Short-...
Anti-angiogenesis therapy for lung cancer:the shore and the other shore Angiogenesis is known to be an important event in tumor growth. In preclinical and clinical researches, anti-angiogenesis therapy has made great progress, ... Z Shuang,J Liu,L Hui,... - 《Oncology and Translational Medici...