Complex polyketides are typically associated with microbial metabolism. Here, we report that animals also make complex, microbe-like polyketides. We show there is a widespread branch of fatty acid synthase- (FAS)-like polyketide synthase (PKS) proteins,
2). Bars can be color-labeled by one or more sample attributes and samples can also be aggregated by these attributes via summing microbe abundances within groups. This is an efficient way for researchers to identify sample- or group-level patterns at various taxonomic levels. Users also have ...
Tunable resistance pulse sensing (tRPS) employs a non-conducting nanomembrane to partition a fluid cell into two sections: a suspension and a particle-free electrolyte [113]. When an electrical potential is applied to move the particles across the nanomembrane, the current between the sections is ...
Chromatin states for bovine, chicken, and pig are from published datasets (Kern et al.2021; Pan et al.2021) (Table2). Chromosomal regions with particular tissue-specific states are shown as thick bars which are labeled with the state according to the specific terminology used in each publicati...
Stable isotope labeled lipids were used as internal standard in order to have comparable results between batches. The obtained results (Fig. 1) show that for a given cell line, lipid distribution is changing over the process. Moreover, this distribution may vary significantly depending on the ...
larger tumors. Enhancing the selectivity of tumor cell irradiation by labeling monoclonal antibodies with nuclides is one approach to cancer therapy. As demonstrated,213Bi-labeled α-particle emitting immunoconjugate had high levels of antigen-selective cytotoxicity when compared to the nonspecific AIC [...
Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2. Mol Cell Biol. 2006;26(22):8336–8346. (Open in a new window)PubMed (Open in a new window)Web of Science ®(Open in a new window)...
Similarly, autophagy promotes, but is not required for amnioserosa basal cell extrusion during dorsal closure stage [60]. Thus, developmental autophagy precedes caspase- dependent amnioserosa cell death, which suggests that autophagy could mediate caspase activation in specific contexts. Autophagy-...
Chronic tinnitus (ringing of the ears) is a medically untreatable condition that reduces quality of life for millions of individuals worldwide. Most cases
For example, dietary fiber can include cell wall materials such as cellulose, hemicelluloses, lignin, and pectins, along with gums and mucilages that are not digested by the body. Dietary fiber includes polysaccharides, oligosaccharides, lignin, and associated plant substances. Soluble and insoluble...