The presence of binding protein(s) of high affinity in the 4 − 5 S region was suggested by the binding of androstanolone, testosterone, 3α—androstanediol and 3β—androstanediol at 0.1 nM concentration. Castration did not seem to affect this binding. ...
Also, there are individuals with a naturally high T/E ratios, perhaps because of other genetic polymorphisms or environmental factors such as excessive alcohol consumption that may increase T/E ratio transiently, particularly in women.129 In the absence of environmental perturbations, the T/E ratio...
The Androgen 5α-Dihydrotestosterone and Its Metabolite 5α-Androstan-3β, 17β-Diol Inhibit the Hypothalamo–Pituitary–Adrenal Response to Stress by Acti... Estrogen receptor β (ERβ) and androgen receptor (AR) are found in high levels within populations of neurons in the hypothalamus. To ...
CRP high-sensitive ELISA 96 3000 德国LABOR DIAGNOSTIKA NORD DME-4700 Neopterin ELISA(新蝶呤) 96 3000 德国LABOR DIAGNOSTIKA NORD Animal Research(AR) 系列ELSIA 试剂盒: 品牌 Catno. Product Det. 价格 德国LABOR DIAGNOSTIKA NORD ARE-8000 Testosterone mouse/rat ELISA(大/小鼠睾酮) ...
We investigated the developmental patterns of 5 alpha-androstane-3 alpha, 17 beta-diol (AD) and 5 alpha-androstane-3 alpha, 17 beta-diol-glucuronide (ADG) in plasma of normal children and adults of both sexes and in patients with idiopathic hirsutism using a physicochemical method: high-resolu...
Urinary T and Adiol were measured using a newly devised technique of high sensitivity and specificity. EXPERIMENTAL PROCEDURE MATERIALS [1,2,6,7-3H]T, [4-14C]T, [I,2-3H]andros;erone (24) and unla- beled steroids (25) were purified on paper chromatography before Collected urine was ...
Preliminary reports of androstanediol glucuronide indicated that it was a peripherally-derived androgen and had a high correlation with clinical gradings of hirsutism. More recent reports have cast doubts on this association. This paper presents an evaluation of the clinical usefulness of androstanediol...
The purification of the plasma extract involved a Sep-Pak; C 18 cartridge and high-performance liquid chromatography. The concentrations (mean ± SD) of the two diols in four normal males are: 213 ± 111 pg/ml for the 3α-diol and 246 ± 133 pg/ml for the 3β-diol....
Reddy DS, Venkatarangan L, Chien B, Ramu K (2005) A high-performance liquid chromatography–tandem mass spectrometry assay of the androgenic neurosteroid 3α-androstanediol (5α-androstane-3α,17β-diol) in plasma. Steroids 70(13):879–885...
IRMS can measure the 13C/12C ratio in compounds with high accuracy and precision [14], [15], [16]. The GC/C/IRMS instrumentation used for determining the 13C/12C ratio of urinary steroids consists of a chromatographic separation by GC, on-line combustion to CO2 and subsequent analysis by...