Hormonal Therapy for Localized and Androgen Deprivation Therapy and Cardiovascular Disease RiskDespite the development of a variety of novel agents for the treatment of advanced and metastatic prostate cancer, the only therapeutic option for this stage of the disease is androgen-deprivation therapy. ...
adjuvant hormonal therapySince Huggins and Hodges demonstrated the responsiveness of prostate cancer to androgen deprivation therapy (ADT), androgen-suppressing strategies have formed the cornerstone of management of advanced prostate cancer. Approaches to ADT have included orchidectomy, oestrogens, luteinizing...
Androgen deprivation therapy (ADT) is an effective hormonal therapy for treating early stages of prostate cancer. The lowering or preventing androgen hormones (testosterone and dihydrotestosterone) from entering into the prostate cells have shown to shrink or slow the growth of the malignant cells. Sev...
Radiation with Hormonal Therapy BSBrock R.Baker, ...MD, MPHRonald C.Chen, inProstate Cancer (Second Edition), 2016 Conclusions Radiation therapy and ADT is a proven combination in the treatment of patients with intermediate-risk, high-risk, and locally advancedprostate cancer. For patients with...
Androgen deprivation therapy has been generally employed in the treatment of locally advanced and metastatic prostate cancer for many years, yet only little data was known about the metabolic syndrome in patients receiving hormonal therapy. This study described the prevalence and the changing trends of...
androgen deprivation therapy Acronyms The use of a gonadotropin-releasing hormone (GnRH) antagonist to treat prostate cancer, which causes characteristic histologic findings that may obscure the diagnosis of residual cancer. Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved. ...
The hypotha- lamic-pituitary-gonadal axis and prostate cancer: implica- tions for androgen deprivation therapy. World J Urol 2014; 32: 669-76.Kluth LA, Shariat SF, Kratzik C et al. The hypothalamic-pituitary- gonadal axis and prostate cancer: implications for androgen deprivation therapy....
In recent years, androgen deprivation therapy has played a greater role in the treatment of prostate cancer. However, androgen suppression can lead to changes in the metabolic profile that increase the risk of cardiovascular disease in men. Evidence is emerging that hormonal therapy increases the ...
Prostate cancer is the second-leading cause of cancer-related mortality in men in Western societies. Androgen receptor (AR) signaling is a critical survival pathway for prostate cancer cells, and androgen-deprivation therapy (ADT) remains the principal t
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