We also discuss the relationship of opioid systems to opioid receptors, and the use of anatomical studies to derive new hypotheses of opioid function and provide dynamic measures of opioid neural activity, especially via specific mRNA quantitation....
J Levine,H Fields,A Basbaum - 《Journal of Neuroscience》 被引量: 832发表: 1993年 Opioid modulation of appetite NeuropeptidesMonoaminesThe discovery of opiate receptors and endogenous opioid peptides within the central nervous system has resulted in a number of ... JE Morley,AS Levine,GK Yim,...
Morphine is metabolized into morphine-6-glucuronide, especially in males, which binds to μ opioid receptors and elicits an analgesic response. Morphine however, also metabolizes in morphine-3-glucuronide, especially in females, which binds to Toll-like receptor 4 and elicits a neuroinflammatory ...
2.1. Periaqueductal gray PAG, Substantia grisea centralis Periaquäduktales Grau Functions: Descending pain suppression (Opioid receptors) S, S, S, Empathy with Pain S Defense, fear S, S, Flight reflex, rage S Blood pressure regulation S Motherly love S, Reproductive behavior S Vocalization ...
Miller's Anatomy of the Dog, 3rd ed 来自 ResearchGate 喜欢 0 阅读量: 28 作者: WP Ireland 摘要: No abstract is available for this article.关键词: Noradrenaline release α-Ad-renoceptors μ- Opioid receptors Presynaptic receptors DOI: 10.1111/j.1748-5827.1994.tb03830.x 被引量: 924 ...
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In many cases, substances such as cocaine, which bind to dopamine receptors, create direct neurobi- ological changes in the operation and GMV of such brain regions25. In behavioral addictions, in contrast, such as addiction to SNS or videogame use, the implicated systems are typically affected...
Opioid Analgesics Human Errors and Human Ills Diuretics Overview Diuretics increase the rate of urine flow and sodium excretion and are used to adjust the volume and/or composition of body fluids in a variety of clinical situations, including hypertension, heart failure, renal failure, nephrotic sy...
1Department of Pharmacology and Physiology, University of Rochester School of Medicine, Rochester, NY, USA; 2Department of Psychology, Stanford University, Stanford, CA, USA Although cells in many brain regions respond to reward, the cortical-basal ganglia circuit is at the heart of the reward ...
“bark” of the adrenal glands) to secrete corticosteroid hormones such as cortisol. ACTH come from a precursor molecule known as pro-opiomelanotropin (POMC) which produces several biologically active molecules when cleaved, including ACTH, melanocyte-stimulating hormone, and the brain opioid peptides...