作者:Christoph, Thomas 出版社:John Wiley & Sons Inc 页数:613 定价:$ 355.95 装帧:HRD ISBN:9783527304035 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到 内容简介· ··· Classified by their mode of action, all important classes of analgesics are presented here, including recent ...
Classified by their mode of action, all important classes of analgesics are presented here, including recent developments that have not yet been introduced to the market. Altogether, more than 300 compounds are described. A carefully designed layout presents the most relevant information at a glance...
and Vane, J.R.: Mode of action of benoxaprofen. Lancet 1: 848 (1984). PubMed CAS Google Scholar Samter, M. and Beers, R.F.Jr: Intolerance to aspirin: Clinical studies and consideration of its pathogenesis. Annals of Internal Medicine 68: 975–983 (1968). PubMed CAS Google Scholar...
出版者:John Wiley & Sons Inc 作者:Christoph, Thomas 出品人: 页数:613 译者: 出版时间: 价格:$ 355.95 装帧:HRD isbn号码:9783527304035 丛书系列: 图书标签: Analgesics 2024 pdf epub mobi 电子书 图书描述 Classified by their mode of action, all important classes of analgesics are presented here, in...
A classification of peripheral analgesics based upon their mode of action This chapter aims to discuss current ideas about the mechanism of action of peripheral analgesics, and to provide a rational basis both for their therapeutic use and for the development of new drugs. The classical explanation...
Mode of action of antipyretic analgesics Inhibition of cyclooxygenase enzymes In 1971, Vane showed that the anti-inflammatory action of NSAIDs rests in their ability to inhibit the activity of the COX enzyme, which in turn results in a diminished synthesis of proinflammatory prostaglandins. This ...
TRPV3 is mentioned here, despite reports of preferential expression in non-neuronal cells. Reduction of keratinocyte ATP release and with that the reduction of sensitization or activation was put forward as mode of action. TRPV3 antagonist GRC15300 was tested in a phase II clinical trial and term...
These data provide insights in the molecular mode of action of the compounds in vivo. If the actions of the compounds in the mouse ‘tetrad’ of neurobehavioral tests were uniquely mediated by CB1receptors, there should have been observed a finding that O-1860 and O-1812 were the most potent...
It is a well known fact that analgesic drugs are capable of inducing bronchospasm in some persons suffering from asthma. Many theories, none of them entirely satisfactory, have been put forward to explain the mechanism of this intolerance. Recent studies of the mode of action of the non steroid...
the site and mode of action of narcotic analgesics, and (3) to speculate on the nature of the heroin abuse problem as it relates to the actions of the narcotic analgesics, as well as on areas of research which may lead to the identification of salient psychopathologic processes in the ...