The International Consensus on ANA Patterns (ICAP) is an ongoing international initiative dedicated to harmonizing technical and interpretation aspects of the HEp-2 IFA test. Comprised of internationally recognized experts in autoimmunity and HEp-2 IFA testing, ICAP has operated for the last 10 years...
Reflecting on a decade of the international consensus on ANA patterns (ICAP): Accomplishments and challenges from the perspective of the 7th ICAP workshop Autoimmunity Reviews Volume 23, Issue 9,September 2024, Page 103608 Purchase options
The article discusses the International Consensus on ANA Patterns (ICAP), which aims to standardize the classification of anti-nuclear antibodies (ANA) patterns in the diagnosis of autoimmune diseases. The ICAP classification system was developed through a series of workshops and has been implemented ...
During the last decade, the International Consensus on ANA Patterns (ICAP) initiative promoted harmonization and understanding of HEp-2 IFA staining pattern nomenclature, as well as promoting their use in patient care by providing interpretation for HEp-2 IFA test results. In conjunction with a ...
The International Consensus on ANA Patterns (ICAP) initiative has previously reached consensus on the nomenclature and definitions of HEp-2 IIFA patterns. In the current paper, the ICAP consensus is presented on the clinical relevance of the 29 distinct HEp-2 IIFA patterns. This clinical relevance...
The International Consensus on ANA Patterns (ICAP) was initiated as a workshop aiming to thoroughly discuss and achieve consensus regarding the morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells. One of the topics discussed at the second ICAP workshop, and ...
ANA pattern for clinical use based on current literature.ResultsConsensus was achieved for 28 ICAP patterns designated with alpha-numeric code (AC-1 to AC-28) and summarised under a nomenclature and classification tree categorised in three major groups (nuclear, cytoplasmic, and mitotic patterns)....
Introduction: Anti-rods and rings (anti-RR) antibodies have recently been described as a cytoplasmic pattern in IIF-based screening of autoantibodies on HEp-2 cells and ICAP has named it as AC-23. It is most frequently related to drug-induced antibody generation. Th...
ICAPAntinuclear antibodies(ANA) are the most common biomarkers observed in autoimmune diseases. Cytoplasmic staining patterns on ANA-Hep-2 are gaining recognition but with scanty information about their clinical and diagnostic role. The aim is to assess the frequency of cytoplasmic ANA patterns in ...
These rare immunofluorescence patterns of autoantibodies on HEp-2 cells defined by ICAP help to identify different autoimmune diseases, including organ-specific and non-organ-specific diseases, in the absence of associated specificities [33]. Likewise, it should be taken into account that we are ...