Lohrisch C, Piccart M. An overview of HER2. Semin Oncol 2001; 28:3-11.Lohrisch C, Piccart M, (ed). An overview of HER2. Seminars in Oncology; 2001: Elsevier.Lohrisch C, Piccart M. An overview of HER2. Semin Oncol. 2001;28:3-11....
The HER2gene expression levelis of clinical significance in correlating with patient prognosis in breast cancer[1]. Higher levels are correlated with poorer prognosis yet successful treatment of breast cancer with the drug Herceptin® is positively correlated with HER2 overexpression, and thus its accu...
© American College of Medical Genetics and Genomics Systematic Review An overview of recommendations and translational milestones for genomic tests in cancer Christine Q. Chang, MPH1, Sharna R. Tingle, MPH1, Kelly K. Filipski, PhD, MPH1, Muin J. Khoury, MD, PhD...
An overview of the clinical and pathological features of tumors and patients included in this study is given in Table 1. After comparative 2-ΔΔCt analyses, we identified a total of 54 miRNAs significantly deregulated in clinical specimens (p|alonge2l(oTf/Nm)i|R >N 1A.0s;wpa ...
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patientsMeta MJ Bourhis - 《Radiotherapy & Oncology》 被引量: 1149发表: 2009年 Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early ...
In this review, we will discuss the synthesis and selection of aptamers for targeted cancer treatment to overcome resistance and reduce side effects from conventional cancer therapy. Additionally, provides an overview of the advances and challenges in aptamer development for using aptamers in cancer tre...
The methods (IHC/FISH) typically used to assess ER, PR, HER2, and Ki67 in FFPE specimens from breast cancer patients are difficult to set up, perform, and
Subsequently, we explored the prognostic and predictive roles of the module and validated the module in clinical samples and cell lines. Our findings suggested that miR-200/183 family-mediated network modules may have potential as biomarker for GC progression. Fig. 1 Overview of our method for ...
Immunohistology, in this context, refers to using fluorescent antibodies that specifically bind to HER2, to estrogen receptor, or to progesterone receptor. From: Clinical Trials (Second Edition), 2016 About this pageSet alert Also in subject area: Nursing and Health ProfessionsDiscover other topics ...
HER2 Gene Amplification and HER2 Protein Overexpression Overexpression of theHER2 proteinis attributable to amplification of the HER2 gene, which is localized onchromosome 17. HER2 overexpression/amplification is usually associated with a high nuclear grade and aggressive disease but also predicts response ...