striatal and thalamic inhibitory interneurons. Dopaminergic nigral neurons are devoid of PNs but are contacted to a different extent by matrix-coated boutons forming subnucleus-specific patterns. A very dense network of ACs is characteristic especially of the posterior lateral cell groups of the ...
Chromosomes stained with certain dyes, commonly quinacrine (Q banding) or Giemsa (G banding), show a pattern of transverse bands of light and heavy staining that is characteristic for the individual chromosome. The basis of the differential staining, which is the same in most tissues, is not ...
Theextracellular matrix(ECM) is a non-cellular macromolecular 3-D network structure, composed ofelastin,fibronectin,laminins, proteoglycans/glycosaminoglycans and otherglycoproteins, as well as numerous soluble factors(67). The matrix components bind to each other and tocell receptors, forming a complex...
The prognosis and prediction of adjuvant chemotherapy (ACT) response in early-stage non-small cell lung cancer (NSCLC) patients remain poor in this era of personalized medicine. We hypothesize that extracellular matrix (ECM)-associated components could b
Dynamic conformational changes play a major role in the function of proteins, including the ATP-Binding Cassette (ABC) transporters. Multidrug Resistance Protein 1 (MRP1) is an ABC exporter that protects cells from toxic molecules. Overexpression of
In the nomogram, each variable is matched to a score and the total score is obtained by summing all variables in each sample. The nomogram plot was evaluated using receiver operating characteristic (ROC) curves. Calibration plot of the nomogram plots was used to describe the similarity between ...
[16], including the grape phylloxera. Confirming these results, our searches of the phylloxera genome revealed that the carotenoid biosynthetic gene cluster is present, as a single copy, and containing the fused phytoene synthase/lycopene cyclase that is characteristic of aphids and of some fungi (...
In the genetic modification of MSCs, a constructed gene cassette is loaded into a vector for easy entry into the MSC. Once inside the MSC, it produces or overexpresses certain specific genes. The transgene expression could either remain constant resulting in characteristic synthesis of specific mole...
7. An approach to molecular characteristic of collagen mesh extracellular matrix in processed tissue banking, by diffractive techniqueIntroduction Preservation techniques are of fundamental support for conservation of tissue banking (TB) biological materials. However, controversial views remain on the effects...
Furthermore, the availability of robust and reliable tools to measure a protein characteristic is of limited utility unless a clinical correlation can be established. There is, for instance, a choice of sensitive and reliable in vitro and ex vivo assays and animal models for determining the ...