Miyabara, S, Bogart, M.H., Winking, H. and Sugihara, H. (1993) Over- growth and enlarged heart in mouse fetuses with maternally inherited Thp and twLub2. An example of genomic imprinting in animals. Cong. Aonom., 33, 63-75.
A considerable number of genetic disorders may not present at birth but appear at varying times throughout life. Some of these may be dominantly inherited and Huntington's Chorea is the best known example. Because of its late onset, usually in early or middle years, those individuals who have...
An example of this is the ABO blood groups where the allele A and allele B are both expressed. If a child inherits an allele A from their mother and an allele B from their father, the individual has blood type AB. Autosomal Recessive Inheritance Autosomal recessive inheritance means that ...
Genomic imprinting is an epigenetic process leading to parental-specific expression of one to two percent of mammalian genes that offers one of the best mo... Barlow,P Denise - 《Annual Review of Genetics》 被引量: 373发表: 2011年 Genomic Imprinting: A Mammalian Epigenetic Discovery Model. Gen...
is on the current problems of the fitness service for elders in 32 communities of 8 cities in term of organization and management,funding,venue facilities,fitness instruction.The methods employed include documents consultation,questionnaire,interview and mathematical statistics.Hopefully,the research can ...
(Supplementary information, Fig.S9a). We took the example of the co-accessible peak pair near theSOX4gene locus to demonstrate this strategy (Supplementary information, Fig.S9b, c). In this way, we identified 3868 pairs of co-accessible peaks from GM12878. Most of the pairs had a good ...
For example, loss of placental imprinting at IGF2 has been associated with reduced placental weight and IUGR17. Similarly, altered methylation has been linked to abnormal placental morphology and pre-term birth18. Intrauterine exposure to the EDC bisphenol A (BPA) markedly alters the methylation of...
The Evolution of Genomic Imprinting In some mammalian genes, the paternally and maternally derived alleles are expressed differently: this phenomenon is called genomic imprinting. Here we stu... A Mochizuki,Y Takeda,Y Iwasa - 《Genetics》 被引量: 193发表: 1996年 Can Molecular Imprinting Explain ...
For example, individuals with Prader-Willi syndrome are most often missing a segment of the paternal copy of chromosome 15. However, if the same segment of chromosome 15 is absent only on the maternal copy of chromosome 15, the individual in question will not have Prader-Willi syndrome, but ...
Cytosine deaminase (CDase) was the first example by catalyzing 5-fluorocytosine (5FC) to a potent anticancer agent, 5-fluorouracil (5FU). 5-FU is a cytotoxic chemotherapy agent frequently used in tumor treatment. One of the advantages of the CD/5-FC system is that it is a targeted ...