名称来源:ALS的学名来源于希腊文“amyotrophia”:其中“a-”表示“不”,“myo”指“肌肉”,trophia意思是“营养”;因此“amyotrophia”表示“没有肌肉营养”,描述了患者肌肉组织的萎缩特征。脊髓横向识别领域是受影响的神经细胞所在部位。在这一地区的退化会导致疤痕或硬化。 别称:运动神经元病(MND),英国常用;法...
由于上位运动神经元变性,脊髓侧索中的皮质脊髓束的轴索消失和萎缩,髓鞘染色其部位浅染。前角和脑神经运动核的下位运动神经元变性,其结果前根或运动神经的轴索消失、萎缩,变成白色。这些神经元支配的骨骼肌中,产生广泛的神经源性的肌纤维萎缩。此病病因及发病机制尚不清楚。 左图为HE染色,可见脊髓的两侧侧索因变性而...
肌萎缩侧索硬化症(amyotrophic lateral sclerosis,ALS) ,俗称“渐冻人症”,是一种以大脑和脊髓运动神经元退行性改变为特征的进行性麻痹性疾病,通常以隐匿性的局部无力起病,然后快速进展至包括膈肌在内的多数肌肉麻痹。 ALS临床表现因受累及存活运动神经元的不同而存在较大的异质性,典型症状为四肢无力起病,但有大约1...
Amyotrophic Lateral Sclerosis (ALS) 肌萎缩性脊髓侧索硬化症 Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease, is an uncommon neurological disorder that primarily impacts motor neurons. As the name suggests, these are nerve cells situated in the brain and spinal cord responsi...
【题目】41 A Amyotrophic lateral sclerosis(ALS)(肌萎缩性侧索硬化症) is a progressiv e neurodegenerat iv e diseas e that affects nerv e cells in th e bra in an d th e spinal cor d. Motor neurons reach f rom th e brain to th e spinal cor d an d from the spinal cor d to ...
肌萎缩侧索硬化(amyotrophiclateralsclerosis,ALS)是一种病因未明、主要累及大脑皮质、脑干和脊髓运动神经元的神经系统变性疾病。其局限性分型包括进行性球麻痹(PBP),连枷臂、腿,进行性肌萎缩(PMA),原发性侧索硬化(PLS)。ALS以进行性发展的骨骼肌萎缩、无力、肌束颤动、延髓麻痹和锥体束征为主要临床表现。一般中老年...
肌萎缩侧索硬化(amyotrophiclateralsclerosis,ALS) 概述肌萎缩侧索硬化(amyotrophiclateralsclerosis,ALS)是一种病因未明、主要累及大脑皮质、脑干和脊髓运动神经元的神经系统变性疾病。其局限性分型包括进行性球麻痹(PBP),连枷臂、腿… 幸孕基因 渐冻人-肌萎缩侧索硬化症的病因研究进展 Doctor莫 重症肌无力|一文读懂重症...
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of motor neurons. As with all major neurodegenerative disorders, development of disease-modifying therapies has proven challenging for multiple reasons. Nevertheless, ALS is one of the few neurodegenerative diseases for whi...
(6分)Amyotrophic lateral sclerosis, more commonly known as ALS, affects the nerve cells in the brain and spinal cord (脊髓) that make the muscles of both the upper and lower body work. Those nerve cells lose their ability to control muscle movement, which leads to paralysis (瘫痪) and ...