Title题目AmyloidPETNet: Classification of Amyloid Positivity in Brain PET Imaging Using End-to-End Deep LearningAmyloidPETNet:使用端到端深度学习对脑PET成像中的淀粉样阳性进行分类01文献速递介绍阿尔茨海默病 (AD) 的一个病理异常是脑内淀粉样蛋白-β (Aβ) 斑块的沉积。淀粉样蛋白PET成像是评估脑内淀粉样...
Title题目AmyloidPETNet: Classification of Amyloid Positivity in Brain PET Imaging Using End-to-End Deep LearningAmyloidPETNet:使用端到端深度学习对脑PET成像中的淀粉样阳性进行分类01文献速递介绍阿尔茨海默病 (AD) 的一个病理异常是脑内淀粉样蛋白-β (Aβ) 斑块的沉积。淀粉样蛋白PET成像是评估脑内淀粉样...
Moreover, Aβ-PET Centiloids (CL) thresholds that can optimally predict functional decline have not yet been established.Cross-sectional and longitudinal analyses over a mean three-year timeframe were performed on the European amyloid-PET imaging AMYPAD-PNHS dataset that phenotypes 1260 individuals,...
Synthesis and 11C﹍abelling of (E,E)3′,4′ヾihydroxystyryl)3′﹎ethoxy﹉ydroxystyryl) benzene for PET imaging of amyloid deposits Carboxylic acid derivatives of the amyloid-binding dye Congo red do not enter the brain well and are thus unable to serve as in vivo amyloid-imaging agent.....
Catafau AM, Bullich S (2015) Amyloid PET imaging: applica- tions beyond Alzheimer's disease. Clin Transl Imaging 3:39-55. doi:10.1007/s40336-014-0098-3Catafau AM, Bullich S (2015) Amyloid PET imaging: applications beyond Alzheimer's disease. Clin Transl Imaging 3: 39-55....
As a biomarker of beta-amyloid, positron emission tomography (PET) amyloid imaging offers a unique opportunity to detect the presence of this protein in the human body during life. Besides Alzheimer’s disease (AD), deposits of beta-amyloid in the brain are also present in other neuro...
Owing to their specificity and high-affinity binding, monoclonal antibodies have potential as positron emission tomography (PET) radioligands and are currently used to image various targets in peripheral organs. However, in the central nervous system, an
Another milestone in the radiological diagnostics of amyloid diseases was the discovery by Klunk and colleagues (University of Pittsburgh, US) of the 11C-labeled PET tracer “Pittsburgh compound B” (PiB) to bind selectively to fibrillar Aβ [90]. This made it possible to reveal amyloid ...
PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 together distinguish Alzheimer's disease from DLB patients Background DLB and AD are frequently confused in clinical practice. Amyloid pathology is required for a diagnosis of AD and is often ...
Table 1 summarizes the demographic, clinical and main amyloid PET imaging data according to the different technics used. The mean MMSE score was of 28.49 at the second follow-up whereas a slight decrement of the continuous cognitive score was observed between inclusion and second follow-up (mean...