Targeting energy pathways in kidney disease: the roles of sirtuins, AMPK, and PGC1 alphaacute kidney injurydiabetic nephropathyfibrosismitochondriaproteinuriaThe kidney has extraordinary metabolic demands to sustain the active transport of solutes that is critical to renal filtration and clearance. ...
ZL006 protects spinal cord neurons against ischemia-induced oxidative stress through AMPK-PGC-1α-Sirt3 pathway (2017). ZL006 protects spinal cord neurons against ischemia-induced oxidative stress through AMPK-PGC-1alpha-Sirt3 pathway. Neurochem. Int. 108, 230-237... SG Liu,YM Wang,YJ Zhang...
NAD+, decreased ADP and AMP contents and the ratio of AMP/ATP, reduced the level of ROS and MDA, enhanced SOD activity, evidently increased the levels of AMPK, SIRT1 and PGC-1 alpha mRNA, up-regulated the expressions of AMPK, pAMPK, SIRT1, PGC-1alpha, NRF1, TFAM and FOXO1 proteins...
The objective of this study is to examine the impact of resveratrol on the activation of the AMP-activated protein kinase/peroxisome proliferator gamma receptor coactivator 1-alpha mechanism of signal pathway on colorectal cancer. Set up blank control group,...
These data suggest that a specific signaling response to LFS is a specific activation of the AMPK-PGC-1alpha signaling pathway which may explain some endurance training adaptations. HFS selectively activates the PKB-TSC2-mTOR cascade causing a prolonged activation of translational regulators, which is...
(2009) Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle . Aging (Albany NY) 1 : 771–783Palacios OM , Carmona JJ , Michan S , Chen KY , Manabe Y , Ward JL 3rd , Goodyear LJ , Tong Q ( 2009 ) Diet and exercise ...
AMPK/PGC-1 alphaSignal pathViralThis study was to investigate the secretion of related factors by alveolar macrophages and AMPK/PGC-1 alpha signal pathway in viral acute lung injury (VALI) patients. 30 SD rats were randomly divided into blank control group (BCG) and VALI group (VALIG) with...
C. L. Zhang, H. Feng, L. Li et al., "Globular CTRP3 pro- motes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1alpha pathway," Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1861, no. 1, Part A, pp. 3085-3094, 2017....
In conclusion, these data suggest that mild HS is sufficient to induce mitochondrial biogenesis associated with activation of the AMPK-SIRT1-PGC-1alpha pathway in C2C12 myotubes. Therefore, it is possible that muscle heat production during exercise plays a role in mitochondrial biogenesis.ChienTing ...
Zhang CL, Feng H, Li L, Wang JY, Wu D, Hao YT, Wang Z, Zhang Y and Wu LL. Globular CTRP3 promotes mitochondrial biogenesis in cardio- myocytes through AMPK/PGC-1alpha pathway. Biochim Biophys Acta 2016; 1861: 3085- 3094.C.-L. Zhang, H. Feng, L. Li, J.-Y. Wang, D. Wu,...